Evidence map›Paper›PMID 36449421›Full record

Trial reportThe New England journal of medicine2022

Trial of Training to Reduce Driver Inattention in Teens with ADHD.

Jeffery N Epstein, Annie A Garner, Adam W Kiefer, James Peugh, Leanne Tamm, Ryan P MacPherson, John O Simon, Donald L Fisher

3 registry-linked trialsOpen access · bronzeAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The New England journal of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02848092 nacompletednot on this map

Improving ADHD Teen Driving

TypeinterventionalSponsorChildren's Hospital Medical Center, CincinnatiRan2016 to 2021Enrolled152ConditionsAttention Deficit Disorder, Attention Deficit Disorder With HyperactivityArmsFOCAL+, Rules of The road
NCT06960980 narecruitingnot on this mapstarted 2025, after this paper: background citation

Improving ADHD Teen Driving - Virtual Reality

TypeinterventionalSponsorChildren's Hospital Medical Center, CincinnatiRan2025 to 2029Enrolled204ConditionsAttention Deficit Hyperactivity Disorder (ADHD)ArmsFOCAL+, VR-FOCAL+
NCT07478458 narecruitingnot on this mapstarted 2025, after this paper: background citation

ADRIS Driving Simulator for Adolescents With Attention Deficit and Hyperactivity Disorder

TypeinterventionalSponsorIstituto Giannina GasliniRan2025 to 2028Enrolled120ConditionsADHD - Attention Deficit Disorder With HyperactivityArmsADRIS-ADHD
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jeffery N EpsteinFrom the Department of Pediatrics, Cincinnati Children's Hospital Medical Center (J.N.E., J.P., L.T., J.O.S.), and the University of Cincinnati College of Medicine (J.N.E., J.P., L.T.) - both in Cincinnati; the Department of Psychology, Saint Louis University, St. Louis (A.A.G.); the Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill (A.W.K., R.P.M.); and the Department of Mechanical and Industrial Engineering, University of Massachusetts, Amherst, and Volpe National Transportation Systems Center, U.S. Department of Transportation, Cambridge - both in Massachusetts (D.L.F.).ORCID 0000-0003-3464-5256
Annie A GarnerFrom the Department of Pediatrics, Cincinnati Children's Hospital Medical Center (J.N.E., J.P., L.T., J.O.S.), and the University of Cincinnati College of Medicine (J.N.E., J.P., L.T.) - both in Cincinnati; the Department of Psychology, Saint Louis University, St. Louis (A.A.G.); the Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill (A.W.K., R.P.M.); and the Department of Mechanical and Industrial Engineering, University of Massachusetts, Amherst, and Volpe National Transportation Systems Center, U.S. Department of Transportation, Cambridge - both in Massachusetts (D.L.F.).
Adam W KieferFrom the Department of Pediatrics, Cincinnati Children's Hospital Medical Center (J.N.E., J.P., L.T., J.O.S.), and the University of Cincinnati College of Medicine (J.N.E., J.P., L.T.) - both in Cincinnati; the Department of Psychology, Saint Louis University, St. Louis (A.A.G.); the Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill (A.W.K., R.P.M.); and the Department of Mechanical and Industrial Engineering, University of Massachusetts, Amherst, and Volpe National Transportation Systems Center, U.S. Department of Transportation, Cambridge - both in Massachusetts (D.L.F.).
James PeughFrom the Department of Pediatrics, Cincinnati Children's Hospital Medical Center (J.N.E., J.P., L.T., J.O.S.), and the University of Cincinnati College of Medicine (J.N.E., J.P., L.T.) - both in Cincinnati; the Department of Psychology, Saint Louis University, St. Louis (A.A.G.); the Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill (A.W.K., R.P.M.); and the Department of Mechanical and Industrial Engineering, University of Massachusetts, Amherst, and Volpe National Transportation Systems Center, U.S. Department of Transportation, Cambridge - both in Massachusetts (D.L.F.).
Leanne TammFrom the Department of Pediatrics, Cincinnati Children's Hospital Medical Center (J.N.E., J.P., L.T., J.O.S.), and the University of Cincinnati College of Medicine (J.N.E., J.P., L.T.) - both in Cincinnati; the Department of Psychology, Saint Louis University, St. Louis (A.A.G.); the Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill (A.W.K., R.P.M.); and the Department of Mechanical and Industrial Engineering, University of Massachusetts, Amherst, and Volpe National Transportation Systems Center, U.S. Department of Transportation, Cambridge - both in Massachusetts (D.L.F.).
Ryan P MacPhersonFrom the Department of Pediatrics, Cincinnati Children's Hospital Medical Center (J.N.E., J.P., L.T., J.O.S.), and the University of Cincinnati College of Medicine (J.N.E., J.P., L.T.) - both in Cincinnati; the Department of Psychology, Saint Louis University, St. Louis (A.A.G.); the Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill (A.W.K., R.P.M.); and the Department of Mechanical and Industrial Engineering, University of Massachusetts, Amherst, and Volpe National Transportation Systems Center, U.S. Department of Transportation, Cambridge - both in Massachusetts (D.L.F.).
John O SimonFrom the Department of Pediatrics, Cincinnati Children's Hospital Medical Center (J.N.E., J.P., L.T., J.O.S.), and the University of Cincinnati College of Medicine (J.N.E., J.P., L.T.) - both in Cincinnati; the Department of Psychology, Saint Louis University, St. Louis (A.A.G.); the Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill (A.W.K., R.P.M.); and the Department of Mechanical and Industrial Engineering, University of Massachusetts, Amherst, and Volpe National Transportation Systems Center, U.S. Department of Transportation, Cambridge - both in Massachusetts (D.L.F.).
Donald L FisherFrom the Department of Pediatrics, Cincinnati Children's Hospital Medical Center (J.N.E., J.P., L.T., J.O.S.), and the University of Cincinnati College of Medicine (J.N.E., J.P., L.T.) - both in Cincinnati; the Department of Psychology, Saint Louis University, St. Louis (A.A.G.); the Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill (A.W.K., R.P.M.); and the Department of Mechanical and Industrial Engineering, University of Massachusetts, Amherst, and Volpe National Transportation Systems Center, U.S. Department of Transportation, Cambridge - both in Massachusetts (D.L.F.).
Cincinnati Children's Hospital Medical Center · USUniversity of North Carolina at Chapel Hill · USSaint Louis University · USUniversity of Massachusetts Amherst · US

Funding

LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., KISSELA, BRETT M · 2015 to 2024
$37.5M
Improving ADHD Teen DrivingR01HD084430 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI JEFF N. EPSTEIN · 2016 to 2026
$4.9M
NCATS NIH HHS 2UL1TR001425NCATS NIH HHS UL1 TR001425NICHD NIH HHS R01 HD084430
6 · The paper itself

Abstract

backgroundTeens with attention deficit-hyperactivity disorder (ADHD) are at increased risk for motor vehicle collisions. A computerized skills-training program to reduce long glances away from the roadway, a contributor to collision risk, may ameliorate driving risks among teens with ADHD.

methodsWe evaluated a computerized skills-training program designed to reduce long glances (lasting ≥2 seconds) away from the roadway in drivers 16 to 19 years of age with ADHD. Participants were randomly assigned in a 1:1 ratio to undergo either enhanced Focused Concentration and Attention Learning, a program that targets reduction in the number of long glances (intervention) or enhanced conventional driver's education (control). The primary outcomes were the number of long glances away from the roadway and the standard deviation of lane position, a measure of lateral movements away from the center of the lane, during two 15-minute simulated drives at baseline and at 1 month and 6 months after training. Secondary outcomes were the rates of long glances and collisions or near-collisions involving abrupt changes in vehicle momentum (g-force event), as assessed with in-vehicle recordings over the 1-year period after training.

resultsDuring simulated driving after training, participants in the intervention group had a mean of 16.5 long glances per drive at 1 month and 15.7 long glances per drive at 6 months, as compared with 28.0 and 27.0 long glances, respectively, in the control group (incidence rate ratio at 1 month, 0.64; 95% confidence interval [CI], 0.52 to 0.76; P<0.001; incidence rate ratio at 6 months, 0.64; 95% CI, 0.52 to 0.76; P<0.001). The standard deviation of lane position (in feet) was 0.98 SD at 1 month and 0.98 SD at 6 months in the intervention group, as compared with 1.20 SD and 1.20 SD, respectively, in the control group (difference at 1 month, -0.21 SD; 95% CI, -0.29 to -0.13; difference at 6 months, -0.22 SD; 95% CI, -0.31 to -0.13; P<0.001 for interaction for both comparisons). During real-world driving over the year after training, the rate of long glances per g-force event was 18.3% in the intervention group and 23.9% in the control group (relative risk, 0.76; 95% CI, 0.61 to 0.92); the rate of collision or near-collision per g-force event was 3.4% and 5.6%, respectively (relative risk, 0.60, 95% CI, 0.41 to 0.89).

conclusionsIn teens with ADHD, a specially designed computerized simulated-driving program with feedback to reduce long glances away from the roadway reduced the frequency of long glances and lessened variation in lane position as compared with a control program. During real-world driving in the year after training, the rate of collisions and near-collisions was lower in the intervention group. (Funded by the National Institutes of Health; ClinicalTrials.gov number, NCT02848092.).

Indexed as

Accidents, TrafficAttention Deficit Disorder with HyperactivityAutomobile DrivingComputer SimulationDistracted DrivingAdolescentAttentionControl GroupsEducationEducational MeasurementHumansPsychomotor PerformanceUnited StatesYoung Adult

Identifiers

PMID36449421
PMCPMC10929260
OpenAlexW4310938030

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.