Evidence map›Paper›PMID 36449269›Full record

ArticleThe American journal of bioethics : AJOB2023

Do Clinicians Have a Duty to Participate in Pragmatic Clinical Trials?

Andrew Garland, Stephanie Morain, Jeremy Sugarman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of bioethics : AJOB, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Is There a Doctor in the House?The American journal of bioethics : AJOB · 2023
    Article
  4. Article
  5. Progressing from "Whether to" to "How to" Conduct Pragmatic Trials.The American journal of bioethics : AJOB · 2023
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Andrew GarlandJohns Hopkins University Berman Institute of Bioethics.ORCID 0000-0001-8649-0976
Stephanie MorainJohns Hopkins University Berman Institute of Bioethics.ORCID 0000-0001-7278-7517
Jeremy SugarmanJohns Hopkins University Berman Institute of Bioethics.ORCID 0000-0001-7022-8332

Funding

NIH Health Care Systems Research Collaboratory-Coordinating Center (U24)U24AT009676 · NCCIH · DUKE UNIVERSITY · PI LESLEY H CURTIS, Adrian Hernandez · 2017 to 2026
$21.5M
HEAL Collaboratory Resource Coordinating Center (PRISM) (U24): Bioethics SupplementU24AT010961 · NCCIH · DUKE UNIVERSITY · PI CURTIS, LESLEY H, HERNANDEZ, ADRIAN · 2019 to 2021
$6.4M
NCCIH NIH HHS U24 AT009676NCCIH NIH HHS U24 AT010961
6 · The paper itself

Abstract

Clinicians have good moral and professional reasons to contribute to pragmatic clinical trials (PCTs). We argue that clinicians have a defeasible duty to participate in this research that takes place in usual care settings and does not involve substantive deviation from their ordinary care practices. However, a variety of countervailing reasons may excuse clinicians from this duty in particular cases. Yet because there is a moral default in favor of participating, clinicians who wish to opt out of this research must justify their refusal. Reasons to refuse include that the trial is badly designed in some way, that the trial activities will violate the clinician's conscience, or that the trial will impose excessive burdens on the clinician.

Indexed as

MoralsPragmatic Clinical Trials as TopicConscienceHumansRefusal to Treatconscientious objectionHealth services researchpragmatic clinical trialsprofessional dutiesprofessional ethicsresearch ethics

Identifiers

PMID36449269
PMCPMC10355327

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.