ArticleJournal of applied physiology (Bethesda, Md. : 1985)2023
Reduced muscle strength in patients with long-COVID-19 syndrome is mediated by limb muscle mass.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Long-term impact of SARS-CoV-2 infection on cardiorespiratory fitness: a meta-analysis.Frontiers in public health · 2023Pooled it
- Trial
- Gastrocnemius electrical stimulation increases ankle dorsiflexion strength in patients with post-acute sequelae of SARS-COV-2 (PASC): a double-blind randomized controlled trial.Scientific reports · 2024Trial
- Article
- Interpreting hand grip strength in hospital employees with post-COVID syndrome compared to non-infected controls: a case-control study.Scientific reports · 2026Article
- Early Postural Instability with History of COVID-19 Influence Related to Diabetes: An Exploratory Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Evaluation of muscle strength and renal function in survivors of severe COVID-19: A 12-month follow-up study.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2026Article
- Persistence of fatigue in the absence of pathophysiological mechanisms in some patients more than 2 years after the original SARS-CoV-2 infection.Experimental physiology · 2026Article
- Long-term multidimensional health status of individuals with and without post COVID-19 condition: A cross-sectional study.PloS one · 2026Article
- Musculoskeletal Sequelae of Post-COVID-19 Syndrome: A Systematic Review.Diseases (Basel, Switzerland) · 2025Review
- Assessment of Bone Mineral Density, Total Body Composition and Joint Integrity in Long COVID: A 12-Month Longitudinal Feasibility Study.Journal of clinical medicine · 2025Article
- Physical activity during COVID-19 pandemic: A 5-year retrospect.Sports medicine and health science · 2025Review
- Sinusoidal exponential distribution for modeling elevated creatinine kinase level as the initial presentation of Covid-19.Scientific reports · 2025Article
- Improvement of Fatigue and Body Composition in Women with Long COVID After Non-Aerobic Therapeutic Exercise Program.Journal of personalized medicine · 2025Article
- Exploring Medium- and Long-Term Respiratory and Functional Sequelae in Young Adults Post-COVID-19.Medicina (Kaunas, Lithuania) · 2025Article
- A Pilot Case-Control Study of Muscle and Bone Health Status in Patients Who Have Recovered From COVID-19 Infection.Cureus · 2024Article
- Health Resort Treatment Improves Functioning and Physical Performance in Long COVID Patients: A Retrospective Study.Healthcare (Basel, Switzerland) · 2024Article
- Musculoskeletal, Pulmonary, and Cardiovascular COVID-19 Sequelae in the Context of Firefighter Occupational Health: A Narrative Review.International journal of environmental research and public health · 2024Review
- Pre-Transplant Dual-Energy X-ray Absorptiometry (DXA)-Derived Body Composition Measures as Predictors of Treatment Outcomes and Early Post-Transplant Complications in Patients with Multiple Myeloma (MM) Treated with Autologous Hematopoietic Stem Cell Transplantation (AutoHSCT).Journal of clinical medicine · 2024Article
- Physical exercise-related manifestations of long COVID: A systematic review and meta-analysis.Journal of exercise science and fitness · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding the impact of COVID-19 on muscle strength may help to elucidate the organ systems that contribute to acute and chronic COVID-19 sequelae. We questioned whether patients with postdischarge symptoms after COVID-19 had compromised muscle strength compared with a control group, and if this potential relationship was mediated by the lower appendicular lean mass index (ALMI). A total of 99 patients with long-COVID-19 and 97 control participants were screened. Maximal grip strength was assessed with a TKK 5101 digital dynamometer, and leg extension 1RM was measured using EGYM Smart Strength machines. Body composition (fat mass percentage, lean mass, visceral fat, and appendicular lean mass index) was determined using a whole body dual-energy X-ray densitometer. Results showed that grip strength and leg extension strength were significantly higher in controls than in COVID-19 survivors (mean [SD], 32.82 [10.01] vs. 26.94 [10.33] kg; difference, 5.87 kg;
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.