ArticleJournal of veterinary science2022
Distribution and genetic diversity of Feline calicivirus in Moscow metropolitan area.
Article in Journal of veterinary science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 8 citations in OpenAlex.
- Localized adaptive evolution in VP1 drives antigenic divergence of feline calicivirus despite high sequence conservation.Veterinary research · 2026Article
- Construction of Reverse Genetics System for Feline Calicivirus FCV-BJ616 and Proteomic Analysis.MicrobiologyOpen · 2026Article
- High Prevalence of Multi-Viral Co-Infections and Low Rabies Seropositivity in Stray Cats of Shenzhen, China.Animals : an open access journal from MDPI · 2025Article
- Epidemiology and Molecular Characterization of Feline Calicivirus in Beijing, China.Animals : an open access journal from MDPI · 2025Article
- Analysis of Genetic Diversity Based on Sequences of Feline Calicivirus Strains Isolated in China.Transboundary and emerging diseases · 2025Article
- Rapid Detection of Feline Calicivirus Using Lateral Flow Dipsticks Based on CRISPR/Cas13a System.Animals : an open access journal from MDPI · 2024Article
- Molecular epidemiology and phylogenetic analysis of feline calicivirus in Kunshan, China.Virology journal · 2024Article
- Use of cutting-edge RNA-sequencing technology to identify biomarkers and potential therapeutic targets in canine and feline cancers and other diseases.Journal of veterinary science · 2023Review
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundFeline calicivirus (FCV) is widespread throughout the world. An FCV infection is associated with conjunctivitis, rhinitis, and mouth ulcers that can lead to the animal's death. Because vaccination is not always effective, it is necessary to monitor the infection regularly.
objectivesThis study examined the FCV epizootic situation in the Moscow metropolitan area by conducting a molecular phylogenetic analysis of the virus isolates.
methodsSamples from 6213 animals were examined by a reverse transcription polymerase chain reaction. For phylogenetic analysis, 12 nucleotide sequences obtained from animal samples were selected. Sequencing was performed using the Sanger method. Phylogenetic analysis was conducted using the Maximum Likelihood method.
resultsThe FCV genome was detected in 1,596 (25.7%) samples out of 6,213. In 2018, calicivirus was detected in 18.9% of samples, 27.8% in 2019, 21.4% in 2020, and 32.6% in 2021. Phylogenetic analysis of the F ORF2 region and the ORF3 start region led to division into two FCV genogroups. Most of the isolates (8 out of 12) were close to the Chinese strains. On the other hand, there were isolates closely related to European and American strains. The isolates circulating in Moscow were not included in clusters with vaccine strains; their nucleotide similarity varied from 77% to 83%.
conclusionsThis study revealed a high prevalence and genetic diversity of the FCV in Moscow. The epizootic situation remains stably tense because 24 viruses were detected in 25% of animals annually.
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