Evidence map›Paper›PMID 36448363›Full record

ArticleThe Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association2024

Establishing a Clinical Protocol for Velopharyngeal MRI and Interpreting Imaging Findings.

Jamie L Perry, Taylor D Snodgrass, Imani R Gilbert, Bradley P Sutton, Adriane L Baylis, Erica M Weidler, Raymond W Tse, Stacey L Ishman, Thomas J Sitzman

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07514091 (MRI Assessment of Velopharyngeal Anatomy in Late Primary Cleft Palate Repair Using Modified Furlow With Buccinator Myomucosal Flap), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07514091 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

MRI Assessment of Velopharyngeal Anatomy in Late Primary Cleft Palate Repair Using Modified Furlow With Buccinator Myomucosal Flap: A Case Series Study

TypeinterventionalSponsorCairo UniversityRan2026 to 2027Enrolled10ConditionsCleft Palate, Cleft Palate, Unilateral, Complete, Cleft Lip, Cleft Alveolus and Cleft Palate, Cleft Palate RepairArmsModified Furlow Palatoplasty combined with buccinator myomucosal flap
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

  1. Diagnostic Utility of Velopharyngeal MRI in Children With Unexplained Velopharyngeal Insufficiency.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  2. Article
  3. Dutch Workflow for Diagnosis and Treatment of Velopharyngeal Insufficiency in Patients with Cleft Palate-A Survey Study.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  4. Management of Persistent Hypernasality After Pharyngeal Flap by Revision Palatoplasty With Use of MRI to Aid Surgical Decision Making.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  5. How Do Nasopharyngoscopy Ratings of Sustained Speech Differ From Connected Speech?The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Observational
  6. The Influence of Age and Sex on the Height of Velopharyngeal Closure.Journal of speech, language, and hearing research : JSLHR · 2025
    Article
  7. Do Palatoplasty Procedures Resolve Hypernasality as Effectively as Pharyngoplasty Procedures in Patients with 22q11.2 Deletion Syndrome?The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2025
    Article
  8. Can MRI Replace Nasopharyngoscopy in the Evaluation of Velopharyngeal Insufficiency?The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2025
    Article
  9. Article
  10. Observational
  11. Review
  12. Levator Veli Palatini Muscle Ratio Is a Clinically Significant Anatomic Predictor for Velopharyngeal Surgical Need.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2025
    Observational
  13. Article
  14. Article
  15. Protocol for a Prospective Observational Study of Revision Palatoplasty Versus Pharyngoplasty for Treatment of Velopharyngeal Insufficiency Following Cleft Palate Repair.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2024
    Article
  16. Article
  17. Article
  18. Sex Differences in Velopharyngeal Anatomy of 9- and 10-Year-Old Children.Journal of speech, language, and hearing research : JSLHR · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Jamie L PerryDepartment of Communication Sciences and Disorders, East Carolina University, Greenville, NC, USA.ORCID 0000-0001-7866-9159
Taylor D SnodgrassDepartment of Communication Sciences and Disorders, East Carolina University, Greenville, NC, USA.ORCID 0000-0001-8315-6016
Imani R GilbertDepartment of Communication Sciences and Disorders, East Carolina University, Greenville, NC, USA.
Bradley P SuttonBioengineering Department, University of Illinois at Urbana Champaign, Urbana, IL, USA.
Adriane L BaylisDepartment of Plastic and Reconstructive Surgery, Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, OH, USA.ORCID 0000-0003-4148-4729
Erica M WeidlerDivision of Plastic Surgery, Phoenix Children's Hospital, Phoenix, AZ, USA.
Raymond W TseDivision of Craniofacial and Plastic Surgery, Department of Surgery, Seattle Children's Hospital, University of Washington, Seattle, WA, USA.
Stacey L IshmanDivision of HealthVine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Thomas J SitzmanDivision of Plastic Surgery, Phoenix Children's Hospital, Phoenix, AZ, USA.ORCID 0000-0002-2173-923X
East Carolina University · USPhoenix Children's Hospital · USCincinnati Children's Hospital Medical Center · USNationwide Children's Hospital · USSeattle Children's Hospital · USUniversity of Illinois Urbana-Champaign · US

Funding

Velopharyngeal insufficiency following cleft palate repair: a comparative effectiveness study of existing surgical procedures and identification of criteria to guide a personalized treatment approachU01DE029750 · NIDCR · PHOENIX CHILDREN'S HOSPITAL · PI SITZMAN, THOMAS JAMES · 2020 to 2024
$4.2M
Using Atlas-driven Imaging for Determining Variations in Velopharyngeal Function Among Children with Cleft Palate and Hypernasal SpeechR01DE027989 · NIDCR · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI PERRY, JAMIE L, SUTTON, BRADLEY P · 2019 to 2022
$2.7M
NIDCR NIH HHS R01 DE027989NIDCR NIH HHS U01 DE029750
6 · The paper itself

Abstract

Traditional imaging modalities used to assess velopharyngeal insufficiency (VPI) do not allow for direct visualization of underlying velopharyngeal (VP) structures and musculature which could impact surgical planning. This limitation can be overcome via structural magnetic resonance imaging (MRI), the only current imaging tool that provides direct visualization of salient VP structures. MRI has been used extensively in research; however, it has had limited clinical use. Factors that restrict clinical use of VP MRI include limited access to optimized VP MRI protocols and uncertainty regarding how to interpret VP MRI findings. The purpose of this paper is to outline a framework for establishing a novel VP MRI scan protocol and to detail the process of interpreting scans of the velopharynx at rest and during speech tasks. Additionally, this paper includes common scan parameters needed to allow for visualization of velopharynx and techniques for the elicitation of speech during scans.

Indexed as

Velopharyngeal InsufficiencyClinical ProtocolsHumansMagnetic Resonance ImagingSpeechinstrumental assessmentmagnetic resonance imagingsecondary surgeryspeech imagingvelopharyngeal insufficiency

Identifiers

PMID36448363
PMCPMC10243551
OpenAlexW4310464227

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.