Evidence map›Paper›PMID 36447872›Full record

ArticleSurgical neurology international2022

Intracranial extramedullary hematopoiesis in a patient with beta-thalassemia presenting with head trauma.

Noah M Nichols, Ashia M Hackett, Alejandro Carrasquilla, Paul Solodnik, Hang Byun, Salazar Jones, Zachary L Hickman

Open access · hybridAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical neurology international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Noah M NicholsDepartment of Neurological Surgery, Icahn School of Medicine at Mount Sinai, New York City, New York, United States.
Ashia M HackettDepartment of Neurological Surgery, Icahn School of Medicine at Mount Sinai, New York City, New York, United States.
Alejandro CarrasquillaDepartment of Neurological Surgery, Icahn School of Medicine at Mount Sinai, New York City, New York, United States.
Paul SolodnikDepartment of Radiology, Icahn School of Medicine at Mount Sinai, New York City, New York, United States.
Hang ByunDepartment of Neurosurgery, Elmhurst Hospital Center, New York City, New York, United States.
Salazar JonesDepartment of Neurological Surgery, Icahn School of Medicine at Mount Sinai, New York City, New York, United States.
Zachary L HickmanDepartment of Neurological Surgery, Icahn School of Medicine at Mount Sinai, New York City, New York, United States.
Icahn School of Medicine at Mount Sinai · USElmhurst Hospital Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Beta-thalassemia is an inherited hemoglobinopathy, whereby reduced or absent expression of beta-globin genes causes impaired erythropoiesis. Extramedullary hematopoiesis (EMH) occurs in 1% of all patients with beta-thalassemia major receiving regular transfusions and is exceedingly rare intracranially. Case Description: We report a case of a male in his 20s with beta thalassemia who presented with head trauma found to have intracranial EMH mimicking multiple extra-axial hematomas. Making the correct diagnosis was critical in avoiding prolonged neuromonitoring and unnecessary interventions. Conclusion: Intracranial extramedullary hematopoietic pseudotumor is an exceedingly rare entity and seldom appears in a neurosurgeon's differential diagnosis. This case illustrates how this condition can easily mimic an acute intracranial hemorrhage in a patient with beta-thalassemia who presents with head trauma. We review the topic to further inform clinicians who may encounter this condition in their practice.

Indexed as

Case reportEpidural hematomaExtramedullary hematopoiesisThalassemiaTraumatic brain injury

Identifiers

PMID36447872
PMCPMC9699845
OpenAlexW4309901747

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.