Evidence map›Paper›PMID 36447798›Full record

ArticleEJIFCC2022

Clinical Thresholds for Pseudohyperkalemia and Pseudonormokalemia in Patients with Thrombocytosis.

Jose Antonio Delgado, Bernardo Lopez, Daniel Morell-García, Eduardo Martínez-Morillo, María Antonieta Ballesteros, Sara Aida Jiménez, María Antonia Durán, Josep Miquel Bauça

Open access · greenAbstract read
In one paragraph

Article in EJIFCC, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jose Antonio DelgadoDepartment of Laboratory Medicine, Hospital Universitari Son Espases, Palma, Spain.
Bernardo LopezDepartment of Hematology, Hospital Universitari Son Espases, Palma, Spain.
Daniel Morell-GarcíaDepartment of Laboratory Medicine, Hospital Universitari Son Espases, Palma, Spain.
Eduardo Martínez-MorilloDepartment of Clinical Biochemistry, Hospital Universitario Miguel Servet, Zaragoza, Spain.
María Antonieta BallesterosDepartment of Laboratory Medicine, Hospital Universitari Son Espases, Palma, Spain.
Sara Aida JiménezDepartment of Hematology, Hospital Universitari Son Espases, Palma, Spain.
María Antonia DuránDepartment of Hematology, Hospital Universitari Son Espases, Palma, Spain.
Josep Miquel BauçaDepartment of Laboratory Medicine, Hospital Universitari Son Espases, Palma, Spain.
Hospital Universitario Son Espases · ESHospital Universitario Miguel Servet · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The lysis of platelets during in vitro coagulation leads to increased potassium concentrations.We aimed to establish the cut-off value for platelet count interfering serum potassium and to estimate the percentage of cases of pseudohyperkalemia and pseudonormokalemia in our hospital. Materials and methods: Individuals diagnosed with essential thrombocytosis (2010-2019) based on the WHO criteria for the classification of myeloid neoplasms and acute leukemia were considered.The cut-off value for the interference of platelet count on serum potassium results was calculated using the reference change value. Sensitivity and specificity were calculated using a ROC-curve, and the size of the effect by the Cohen's d.The clinical impact of both phenomena was assessed by reviewing the medical records of individuals classified as such, and also looking for potential cases in 2019 on the laboratory information system. Results: Fifty-four individuals with essential thrombocytosis were included. Potassium concentration correlated with platelet count (P-value<0.001; Spearman's ρ =0.394) in serum. The cut-off value of platelet count interfering potassium was 598x10 Conclusion: This study provides a cut-off value for platelet count interfering serum potassium concentrations, and brings to light not only pseudohyperkalemia-related issues, but also the pseudonormokalemia phenomenon, which usually goes unnoticed.

Indexed as

cut-offhyperkalemiainterferenceplateletpotassium

Identifiers

PMID36447798
PMCPMC9644095
OpenAlexW4310602551

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.