ArticleJournal of the Belgian Society of Radiology2022
Multidetector Computed Tomographic Evaluation of the Normal Characteristics of the Thymus in the Pediatric Population.
Article in Journal of the Belgian Society of Radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Thymic hyperplasia in patients with acromegaly: imaging-based assessment and clinical implications.Archives of endocrinology and metabolism · 2026Article
- The embryologic footprint of the thymus: study by imaging.Pediatric radiology · 2026Review
- Thymic evolution on serial CT in glucocorticoid-treated pediatric pneumonia: a retrospective analysis.BMC pediatrics · 2026Article
- Thymic Hyperplasias in Practice: Clinical Context, Histological Clues, and Management Implications.Cancers · 2025Review
- Mediastinal lesions in children.World journal of clinical cases · 2023Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: The objective of the present study was to determine the morphologic features and measurements of the normal thymus on contrast-enhanced multi-detector computed tomography (MDCT) in subjects from the newborn period up to 18 years of age. Materials and Methods: The MDCT scans obtained from 464 children with a mean age ± SD of 8.43 ± 5.60 years were retrospectively re-evaluated. The shape, margins, side predominance, density, and measurements of the thymic gland were defined for each age group. Results: A triangular thymic shape with a middle location and straight lateral contours were the most frequently seen morphologic features in children. The mean anteroposterior and transverse diameter of the thymus was 17.32 ± 4.58 and 29.99 ± 11.42 mm, respectively. The mean values for the width and thickness were 20.66 ± 5.36 and 15.15 ± 6.76 mm for the right thymic lobe, respectively; and 26.14 ± 7.85 and 14.91 ± 5.51 mm for the left, respectively. The transverse diameter of the thymus and thymic lobe dimensions decreased significantly with age, however, the anteroposterior diameter of the thymus was not significantly associated with age. Girls had higher mean thymic attenuation values compared to boys, however, this gender difference was not statistically significant (63.8 ± 22.4 HU vs. 60.1 ± 25.3, p = 0.164). Conclusion: Our study provides a better understanding of the normal thymic appearances in children that can aid in accurate diagnosis and avoid unnecessary, costly, and invasive interventions.
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