Trial reportClinical interventions in aging2022
Effects of Immersive Virtual Therapy as a Method Supporting Recovery of Depressive Symptoms in Post-Stroke Rehabilitation: Randomized Controlled Trial.
Trial report in Clinical interventions in aging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 32 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Effectiveness of the "VRTierOne" Virtual Therapeutic Game as a Method Supporting the Post-stroke Rehabilitation
Does Immersive Virtual Reality Therapy Support Orthopedic Rehabilitation? A Randomized-Controlled Trial
Who cites it
32 citing papers in PubMed, 9 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- The improvement effects and mechanisms of virtual reality training on depression: a systematic review from a neurotransmitter-plasticity dual-pathway perspective.Journal of global health · 2026Pooled it
- Virtual reality for stroke rehabilitation.The Cochrane database of systematic reviews · 2025Pooled it
- Effectiveness of Virtual Reality Training in Improving Outcomes for Dialysis Patients: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Research hotspots and trends of post-stroke depression rehabilitation: a bibliometric analysis from 2003 to 2024.Frontiers in neurology · 2025Pooled it
- Evaluating virtual reality technology in psychotherapy: impacts on anxiety, depression, and ADHD.Frontiers in psychiatry · 2024Pooled it
- Pooled it
- Acceptability, Feasibility, and Effectiveness of Immersive Virtual Technologies to Promote Exercise in Older Adults: A Systematic Review and Meta-Analysis.Sensors (Basel, Switzerland) · 2023Pooled it
- Immersive Virtual Reality in Post-Stroke Rehabilitation: A Systematic Review.Sensors (Basel, Switzerland) · 2023Pooled it
- Pooled it
- Effects of Immersive Virtual Therapy as a Method Supporting the Psychological and Physical Well-Being of Women with a Breast Cancer Diagnosis: A Randomized Controlled Trial.Current oncology (Toronto, Ont.) · 2024Trial
- Efficacy of the use of video games on mood, anxiety and depression in stroke patients: preliminary findings of a randomised controlled trial.Journal of neurology · 2024Trial
- Virtual Reality-Assisted Rehabilitation for Upper-Limb Function in Stroke Survivors: A Systematic Review.Brain sciences · 2026Review
- "Your Digital Doctor Will Now See You": A Narrative Review of VR and AI Technology in Chronic Illness Management.Healthcare (Basel, Switzerland) · 2026Review
- Immersive metaverse art as a psychological intervention for depression and anxiety: a narrative review and multilevel model integrating engagement, cultural identity, and neurocognitive mechanisms.Frontiers in psychology · 2026Review
- Immersive virtual reality-based intervention for psychological wellbeing among older adults: A systematic review and meta-analysis.PLOS digital health · 2026Article
- Mechanisms of Virtual Reality-Based Relaxation in Older Adults: A Scoping Review.Journal of clinical medicine · 2025Review
- The Effect of Immersion Technology on the Quality of Life in Older Adults: A Systematic Review.Aging medicine (Milton (N.S.W)) · 2025Article
- The Role of Astrocytes in Poststroke Rehabilitation.Brain and behavior · 2025Review
- Effects of immersive virtual therapy on psychological and physical wellbeing in women with breast cancer at different stages of disease and treatment conditions: an experimental comparative study.Frontiers in oncology · 2025Article
- Analysis of Factors Affecting Quality of Life (QoL) in Middle-Aged Stroke Patients (Under 65 Years Old) in the Rehabilitation Phase: Multivariate Regression Analysis.Journal of multidisciplinary healthcare · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Depressive symptoms constitute an important group of mental problems that alter the course of post-stroke rehabilitation by reducing quality of life, physical activity, social functioning, and interpersonal relationships. Although several studies have shown the efficacy of virtual reality (VR) in the motor treatment of poststroke patients, there is a lack of studies that would also evaluate the impact of VR on psychological aspects. Thus, we investigated the effectiveness of immersive VR therapy on both functional activity and depressive symptoms in stroke survivors. Patients and Methods: We conducted a single blind, randomized controlled trial comparing VR therapy with Schultz's Autogenic Training (SAT). Patients randomized to the VR group received treatment in an immersive VR therapeutic garden with elements of psychotherapy and physical activity of the upper extremities, whereas patients in the control group received SAT. Additionally, patients in both groups received standard neurological rehabilitation. The full research cycle lasted six weeks. We used Geriatric Depression Scale, Generalized Self-Efficacy Scale, Acceptance of Illness Scale, Visual Analogue Scale of pain, Hospital Anxiety and Depression Scale, Barthel Index, Lawton Instrumental Activities of Daily Living Scale and Rivermead Motor Assessment for outcome assessment. This trial was registered with ClinicalTrials.gov (NCT03830372). Results: We assessed 60 patients and randomly assigned to the VR or control group. The VR group showed a significant reduction in depressive symptoms (ηp Conclusion: The use of VR therapy combined with neurological rehabilitation had a positive effect on improving mood and reducing depressive symptoms in post-stroke patients.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.