ReviewTobacco induced diseases2022
Is electronic cigarette use a risk factor for stroke? A systematic review and meta-analysis.
Review in Tobacco induced diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Are electronic cigarettes associated with the risk of myocardial infarction and stroke? A systematic review and meta-analysis.BMC public health · 2025Pooled it
- Health impacts of electronic nicotine delivery systems: an umbrella review of systematic reviews.BMJ open · 2025Pooled it
- Electronic cigarette use, related health outcomes and policy interventions in the USA: a call for research to fill evidence gaps.Tobacco control · 2026Review
- Cardiovascular Risk Among Stroke Survivors With Combustible and Electronic Cigarettes: A Nationwide Study in Korean Men.Journal of the American Heart Association · 2026Article
- Multisystem Toxicity of E-Cigarettes in Preclinical and Clinical Studies: Pathophysiologic Effects of E-Cigarette Aerosol Exposures from Head to Toe.Annual review of pharmacology and toxicology · 2026Review
- Electronic cigarettes and cardiovascular diseases: An updated systematic review and network meta-analysis.Tobacco induced diseases · 2025Review
- Lifestyle behaviors and cardiovascular risk factors in transgender versus cisgender stroke survivors.PloS one · 2025Article
- The association between combustible/electronic cigarette use and stroke based on national health and nutrition examination survey.BMC public health · 2023Article
- Association between electronic nicotine delivery systems use and risk of stroke: a meta-analysis of 1,024,401 participants.Archives of medical science : AMS · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionStroke, as a common cerebrovascular disease, has a high mortality and disability rate. Although many studies have reported that using e-cigarettes was associated with occurrence of stroke, some studies have concluded that e-cigarettes may help smokers stop using combustible cigarettes and reduce the risk of stroke. Therefore, we aimed to validate the hypothesis that e-cigarette use might be an independent risk factor for stroke occurrence by performing a systematic review and meta-analysis of clinical epidemiology studies.
methodsThe pooled effect was calculated by the random effects model. I
resultsSix cross-sectional studies with high quality were finally included in the meta-analysis, which included a total of 1134896 participants. Analysis with random effects model showed that the total pooled odds ratio (OR) of stroke occurrence in e-cigarette users was 1.25 (95% CI: 1.01-1.55) (I
conclusionsThe role of e-cigarette use in the development of stroke is inconclusive, due to the strong effect of prior tobacco use as a risk factor for stroke in the included studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.