Evidence map›Paper›PMID 36447267›Full record

ReviewVirology journal2022

Human herpesvirus 7 encephalitis in an immunocompetent adult and a literature review.

Yi Li, Tianhao Qu, Dandan Li, Juanjuan Jing, Qiuming Deng, Xianyao Wan

Open access · goldAbstract readReviewCase Reports
In one paragraph

Review in Virology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yi Li *Department of Critical Care Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, 116021, China.
Tianhao Qu *Department of Oncology, The First Affiliated Hospital of Dalian Medical University, Dalian, 116021, China.
Dandan LiDepartment of Critical Care Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, 116021, China.
Juanjuan JingDepartment of Critical Care Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, 116021, China.
Qiuming DengDepartment of Critical Care Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, 116021, China. 13898429300@163.com.
Xianyao WanDepartment of Critical Care Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, 116021, China. 13322210199@163.com.
Dalian Medical University · CNFirst Affiliated Hospital of Dalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman herpesvirus 7 (HHV-7) is a common virus that infects children early and is accompanied by lifelong latency in cells, which is easy to reactivate in immunodeficient adults, but the underlying pathological mechanism is uncertain in immunocompetent adults without peculiar past medical history. Even though the clinical manifestation of the encephalitis caused by HHV-7 is uncommon in immunocompetent adults, the HHV-7 infection should not be neglected for encephalitis for unknown reasons. CASE PRESENTATION: We reported here a case of HHV-7 encephalitis with epileptic seizures. While the brain computer tomography was standard, electroencephalography displayed slow waves in the temporal and bilateral frontal areas, then HHV-7 DNA was detected in the metagenomic next-generation sequencing of cerebrospinal fluid. Fortunately, the patient recovered after treatment and was discharged 2 months later. We also collected the related cases and explored a better way to illuminate the underlying mechanism.

conclusionThe case indicates clinicians should memorize HHV-7 as an unusual etiology of encephalitis to make an early diagnosis and therapy.

Indexed as

Encephalitis, Herpes SimplexHerpesvirus 7, HumanRoseolovirus InfectionsAdultChildElectroencephalographyHigh-Throughput Nucleotide SequencingHumansEncephalitisEpileptic seizuresHHV-7Immunocompetent adult

Identifiers

PMID36447267
PMCPMC9707246
OpenAlexW4310263434

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.