Evidence map›Paper›PMID 36447150›Full record

ArticleBMC pregnancy and childbirth2022

Artificial rupture of membranes as a mode for induction of labor in women with a previous cesarean section- a retrospective cohort study.

Aharon Dick, Einat Gutman-Ido, Henry Hillel Chill, Gilad Karavani, Ina Ryvkin, Shay Porat, Joshua Isaac Rosenbloom

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pregnancy and childbirth, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Aharon DickDepartment of Obstetrics and Gynecology, Hadassah Medical Center and Hebrew University of Jerusalem, Jerusalem, Israel. Aharondick88@gmail.com.
Einat Gutman-IdoDepartment of Obstetrics and Gynecology, Hadassah Medical Center and Hebrew University of Jerusalem, Jerusalem, Israel.
Henry Hillel ChillDivision of Urogynecology, University of Chicago Pritzker School of Medicine, NorthShore University HealthSystem, Skokie, IL, USA.
Gilad KaravaniDepartment of Obstetrics and Gynecology, Hadassah Medical Center and Hebrew University of Jerusalem, Jerusalem, Israel.
Ina RyvkinDepartment of Obstetrics and Gynecology, Hadassah Medical Center and Hebrew University of Jerusalem, Jerusalem, Israel.
Shay PoratDepartment of Obstetrics and Gynecology, Hadassah Medical Center and Hebrew University of Jerusalem, Jerusalem, Israel.
Joshua Isaac RosenbloomDepartment of Obstetrics and Gynecology, Hadassah Medical Center and Hebrew University of Jerusalem, Jerusalem, Israel.
Hebrew University of Jerusalem · ILHadassah Medical Center · ILNorthShore University HealthSystem · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInduction of labor in women with a previous cesarean section (CS) is associated with increased rates of uterine rupture and failed attempt for vaginal delivery. Prostaglandins use is contraindicated in this population, limiting available options for cervical ripening.

objectiveTo evaluate the efficacy and safety of artificial rupture of membranes (AROM) as a mode of Induction of labor (IOL) in women with a previous cesarean section.

methodsA retrospective cohort study conducted in a single tertiary care center between January 2015 and October 2020. Women with one previous cesarean section and a current singleton term pregnancy requiring IOL, with an unfavorable cervix, were included. The primary outcome was a successful vaginal delivery (VBAC); secondary outcomes were rates of chorioamnionitis, uterine rupture and low Apgar score (< 7).

resultsOf the 665 women who met the inclusion criteria, 492 (74%) did not receive subsequent oxytocin and 173 (26%) did. There were significant differences in the baseline characteristics between these two groups, including maternal age, cervical dilation at presentation, parity, and a history of a previous VBAC. Among women who were induced solely by AROM the rate of a successful TOLAC was higher (81.3% vs 73.9%), total time of IOL was shorter (mean 8.7 h vs.16.1 h) and the risk of chorioamnionitis was lower (7.3% vs 18.4%). When subdividing the women who received oxytocin into early (< 12 h after AROM) vs late (> 12 h after AROM) administration, there were no significant changes in the rates of successful VBAC or of chorioamnionitis.

conclusionAROM as a single mode of IOL in women with a previous CS is a safe and efficient practice with high rates of successful VBAC. When spontaneous labor does not develop, there is no advantage to delay the administration of oxytocin.

Indexed as

ChorioamnionitisUterine RuptureAmniotomyCervical RipeningCesarean SectionFemaleHumansLabor, InducedOxytocinPregnancyRetrospective StudiesOxytocinAmniotomyArtificial rupture of membranes (AROM)Induction of Labor (IOL)OxytocinTrial of labor after cesarean section (TOLAC)Vaginal birth after cesarean (VBAC)

Identifiers

PMID36447150
PMCPMC9710010
OpenAlexW4310591262

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.