Evidence map›Paper›PMID 36446998›Full record

ArticleBrain topography2023

Topographic Mapping of the Primary Sensory Cortex Using Intraoperative Optical Imaging and Tactile Irritation.

Witold H Polanski, Martin Oelschlägel, Tareq A Juratli, Hannes Wahl, Pawel M Krukowski, Ute Morgenstern, Edmund Koch, Gerald Steiner, Gabriele Schackert, Stephan B Sobottka

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain topography, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Biomedical optics express · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Witold H PolanskiDepartment of Neurosurgery, University Hospital of Dresden, Fiedlerstr. 74, 01307, Dresden, Germany. Witold.polanski@uniklinikum-dresden.de.ORCID 0000-0002-6603-5375
Martin OelschlägelClinical Sensoring and Monitoring, Faculty of Medicine, University Hospital Carl Gustav Carus, Dresden University of Technology, 01307, Dresden, Germany.
Tareq A JuratliDepartment of Neurosurgery, University Hospital of Dresden, Fiedlerstr. 74, 01307, Dresden, Germany.
Hannes WahlInstitute of Diagnostic and Interventional Neuroradiology, University Hospital Carl Gustav Carus, Technical University of Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Pawel M KrukowskiInstitute of Diagnostic and Interventional Neuroradiology, University Hospital Carl Gustav Carus, Technical University of Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Ute MorgensternInstitute of Biomedical Engineering, Faculty of Electrical and Computer Engineering, Technische Universität Dresden, 01307, Dresden, Germany.
Edmund KochClinical Sensoring and Monitoring, Faculty of Medicine, University Hospital Carl Gustav Carus, Dresden University of Technology, 01307, Dresden, Germany.
Gerald SteinerClinical Sensoring and Monitoring, Faculty of Medicine, University Hospital Carl Gustav Carus, Dresden University of Technology, 01307, Dresden, Germany.
Gabriele SchackertDepartment of Neurosurgery, University Hospital of Dresden, Fiedlerstr. 74, 01307, Dresden, Germany.
Stephan B SobottkaDepartment of Neurosurgery, University Hospital of Dresden, Fiedlerstr. 74, 01307, Dresden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The determination of exact tumor boundaries within eloquent brain regions is essential to maximize the extent of resection. Recent studies showed that intraoperative optical imaging (IOI) combined with median nerve stimulation is a helpful tool for visualization of the primary sensory cortex (PSC). In this technical note, we describe a novel approach of using IOI with painless tactile irritation to demonstrate the feasibility of topographic mapping of different body regions within the PSC. In addition, we compared the IOI results with preoperative functional MRI (fMRI) findings. In five patients with tumors located near the PSC who received tumor removal, IOI with tactile irritation of different body parts and fMRI was applied. We showed that tactile irritation of the hand in local and general anesthesia leads to reliable changes of cerebral blood volume during IOI. Hereby, we observed comparable IOI activation maps regarding the median nerve stimulation, fMRI and tactile irritation of the hand. The tactile irritation of different body areas revealed a plausible topographic distribution along the PSC. With this approach, IOI is also suitable for awake surgeries, since the tactile irritation is painless compared with median nerve stimulation and is congruent to fMRI findings. Further studies are ongoing to standardize this method to enable a broad application within the neurosurgical community.

Indexed as

Brain NeoplasmsGliomaBrainBrain MappingCerebral CortexHumansMagnetic Resonance ImagingFunctional MRIIntraoperative optical imagingSensory irritation

Identifiers

PMID36446998
PMCPMC9834102

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.