ArticleScientific reports2022
Ultrafast laser surgery probe for sub-surface ablation to enable biomaterial injection in vocal folds.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 13 citations in OpenAlex.
- Emerging ultrafast technologies in biotechnology.3 Biotech · 2025Review
- Ultrafast laser bone ablation towards high surgical speeds and clinically relevant operation times for spine surgeries.Biomedical optics express · 2025Article
- Two photon imaging probe with highly efficient autofluorescence collection at high scattering and deep imaging conditions.Biomedical optics express · 2024Article
- Ultrafast Laser Microlaryngeal Surgery for In Vivo Subepithelial Void Creation in Canine Vocal Folds.The Laryngoscope · 2023Article
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
Creation of sub-epithelial voids within scarred vocal folds via ultrafast laser ablation may help in localization of injectable therapeutic biomaterials towards an improved treatment for vocal fold scarring. Several ultrafast laser surgery probes have been developed for precise ablation of surface tissues; however, these probes lack the tight beam focusing required for sub-surface ablation in highly scattering tissues such as vocal folds. Here, we present a miniaturized ultrafast laser surgery probe designed to perform sub-epithelial ablation in vocal folds. The requirement of high numerical aperture for sub-surface ablation, in addition to the small form factor and side-firing architecture required for clinical use, made for a challenging optical design. An Inhibited Coupling guiding Kagome hollow core photonic crystal fiber delivered micro-Joule level ultrashort pulses from a high repetition rate fiber laser towards a custom-built miniaturized objective, producing a 1/e
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