Evidence map›Paper›PMID 36446773›Full record

ArticleNature communications2022

Deficiency and excess of groundwater iodine and their health associations.

Ruoqi Ma, Mingquan Yan, Peng Han, Ting Wang, Bin Li, Shungui Zhou, Tong Zheng, Yandi Hu, Alistair G L Borthwick, Chunmiao Zheng and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 88 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Bioinspired Microreactor for Iodide Adsorption and Photooxidation Recovery.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Climate changes affecting global iodine status.European thyroid journal · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

Ruoqi MaCollege of Environmental Sciences and Engineering, Peking University; Key Laboratory of Water and Sediment Sciences, Ministry of Education, Beijing, 100871, P. R. China.ORCID 0000-0002-8592-6480
Mingquan YanCollege of Environmental Sciences and Engineering, Peking University; Key Laboratory of Water and Sediment Sciences, Ministry of Education, Beijing, 100871, P. R. China.
Peng HanCollege of Environmental Sciences and Engineering, Peking University; Key Laboratory of Water and Sediment Sciences, Ministry of Education, Beijing, 100871, P. R. China.
Ting WangCollege of Environmental Sciences and Engineering, Peking University; Key Laboratory of Water and Sediment Sciences, Ministry of Education, Beijing, 100871, P. R. China.
Bin LiCollege of Environmental Sciences and Engineering, Peking University; Key Laboratory of Water and Sediment Sciences, Ministry of Education, Beijing, 100871, P. R. China.ORCID 0000-0001-9172-2516
Shungui ZhouProvincial Key Laboratory of Soil Environment Health and Regulation, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China.ORCID 0000-0003-0899-4225
Tong ZhengCollege of Environmental Sciences and Engineering, Peking University; Key Laboratory of Water and Sediment Sciences, Ministry of Education, Beijing, 100871, P. R. China.ORCID 0000-0002-2606-3160
Yandi HuCollege of Environmental Sciences and Engineering, Peking University; Key Laboratory of Water and Sediment Sciences, Ministry of Education, Beijing, 100871, P. R. China.
Alistair G L BorthwickInstitute of Infrastructure and Environment, School of Engineering, The University of Edinburgh, Edinburgh, EH9 3JL, UK.ORCID 0000-0001-6053-7764
Chunmiao ZhengState Environmental Protection Key Laboratory for Integrated Control of Groundwater and Surface Water Pollution in Watershed, Southern University of Science and Technology, Shenzhen, 518055, P. R. China.ORCID 0000-0001-5839-1305
Jinren NiCollege of Environmental Sciences and Engineering, Peking University; Key Laboratory of Water and Sediment Sciences, Ministry of Education, Beijing, 100871, P. R. China. jinrenni@pku.edu.cn.ORCID 0000-0002-9114-8347
Peking University · CNFujian Agriculture and Forestry University · CNSouthern University of Science and Technology · CNUniversity of Plymouth · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

More than two billion people worldwide have suffered thyroid disorders from either iodine deficiency or excess. By creating the national map of groundwater iodine throughout China, we reveal the spatial responses of diverse health risks to iodine in continental groundwater. Greater non-carcinogenic risks relevant to lower iodine more likely occur in the areas of higher altitude, while those associated with high groundwater iodine are concentrated in the areas suffered from transgressions enhanced by land over-use and intensive anthropogenic overexploitation. The potential roles of groundwater iodine species are also explored: iodide might be associated with subclinical hypothyroidism particularly in higher iodine regions, whereas iodate impacts on thyroid risks in presence of universal salt iodization exhibit high uncertainties in lower iodine regions. This implies that accurate iodine supply depending on spatial heterogeneity and dietary iodine structure optimization are highly needed to mitigate thyroid risks in iodine-deficient and -excess areas globally.

Indexed as

GroundwaterIodineHumansIodidesSodium Chloride, DietaryThyroid GlandIodidesIodineSodium Chloride, Dietary

Identifiers

PMID36446773
PMCPMC9708681
OpenAlexW4310596784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.