Evidence map›Paper›PMID 36446585›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2023

Establishment and Application of a Novel

Ning Liu, Yadan Li, Yinghua Jiang, Samuel Shi, Aim Niamnud, Sammy J Vodovoz, Prasad V G Katakam, Charles Vidoudez, Aaron S Dumont, Xiaoying Wang

Open access · greenAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

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  9. Tracing the path of disruption:CNS neuroscience & therapeutics · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ning LiuClinical Neuroscience Research Center, Department of Neurosurgery and Neurology, Tulane University School of Medicine, New Orleans, Louisiana 70122 nliu3@tulane.edu xwang51@tulane.edu.ORCID 0000-0002-5632-0359
Yadan LiClinical Neuroscience Research Center, Department of Neurosurgery and Neurology, Tulane University School of Medicine, New Orleans, Louisiana 70122.
Yinghua JiangClinical Neuroscience Research Center, Department of Neurosurgery and Neurology, Tulane University School of Medicine, New Orleans, Louisiana 70122.
Samuel ShiClinical Neuroscience Research Center, Department of Neurosurgery and Neurology, Tulane University School of Medicine, New Orleans, Louisiana 70122.
Aim NiamnudClinical Neuroscience Research Center, Department of Neurosurgery and Neurology, Tulane University School of Medicine, New Orleans, Louisiana 70122.
Sammy J VodovozClinical Neuroscience Research Center, Department of Neurosurgery and Neurology, Tulane University School of Medicine, New Orleans, Louisiana 70122.
Prasad V G KatakamClinical Neuroscience Research Center, Department of Neurosurgery and Neurology, Tulane University School of Medicine, New Orleans, Louisiana 70122.
Charles VidoudezHarvard Center for Mass Spectrometry, Harvard University, Cambridge, Massachusetts 02138.
Aaron S DumontClinical Neuroscience Research Center, Department of Neurosurgery and Neurology, Tulane University School of Medicine, New Orleans, Louisiana 70122.
Xiaoying WangClinical Neuroscience Research Center, Department of Neurosurgery and Neurology, Tulane University School of Medicine, New Orleans, Louisiana 70122 nliu3@tulane.edu xwang51@tulane.edu.
Tulane University · USHarvard University · US

Funding

Peroxynitrite is a Molecular Determinant of Impaired Microvascular Energetics in Alzheimer's DiseaseR01AG074489 · NIA · TULANE UNIVERSITY OF LOUISIANA · PI KATAKAM, PRASAD V, MOSTANY, RICARDO · 2021 to 2025
$3.2M
Cerebral Microvascular Bioenergetics and Neurovascular CouplingR01NS114286 · NINDS · TULANE UNIVERSITY OF LOUISIANA · PI KATAKAM, PRASAD V, MOSTANY, RICARDO · 2020 to 2024
$2.5M
Annexin A2 as a cerebrovascular therapy in traumatic brain injuryR01NS092085 · NINDS · TULANE UNIVERSITY OF LOUISIANA · PI WANG, XIAOYING · 2015 to 2019
$1.9M
Role of Irg-1/itaconate in modulating secondary brain damage after traumatic brain injury in miceR01NS126503 · NINDS · TULANE UNIVERSITY OF LOUISIANA · PI XIAOYING WANG · 2023 to 2026
$1.7M
NIA NIH HHS R01 AG074489NINDS NIH HHS R01 NS092085NINDS NIH HHS R01 NS114286NINDS NIH HHS R01 NS126503
6 · The paper itself

Abstract

Mechanical impact-induced primary injury after traumatic brain injury (TBI) leads to acute microglial pro-inflammatory activation and consequently mediates neurodegeneration, which is a major secondary brain injury mechanism. However, the detailed pathologic cascades have not been fully elucidated, partially because of the pathologic complexity in animal TBI models. Although there are several

Indexed as

Brain Injuries, TraumaticMicrogliaAnimalsMacrophagesMaleMiceMice, Inbred C57BLNeuronsin vitro modelmetabolic reprogrammingmicroglia and neuron coculturemicroglial pro-inflammatory activationneuronal injurytraumatic brain injury

Identifiers

PMID36446585
PMCPMC9838700
OpenAlexW4310457472

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.