Evidence map›Paper›PMID 36445669›Full record

ArticleThe international journal of cardiovascular imaging2022

Coronary CT angiography and serum biomarkers are potential biomarkers for predicting MACE at three-months and one-year follow-up.

Honglei Huang, Fei Ye, Yuanmao Huang, Guiyun Ye, Jiarui Zhu, Xidi Chi, Gaofeng Zhang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The international journal of cardiovascular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Honglei HuangDepartment of Radiology, The Affiliated Nanping First Hospital of Fujian Medical University, Nanping, China.
Fei YeDepartment of Radiology, The Affiliated Nanping First Hospital of Fujian Medical University, Nanping, China.
Yuanmao HuangDepartment of Laboratory, The Affiliated Nanping First Hospital of Fujian Medical University, Nanping, China.
Guiyun YeDepartment of Laboratory, The Affiliated Nanping First Hospital of Fujian Medical University, Nanping, China. ygycljygyclj@163.com.
Jiarui ZhuDepartment of Laboratory, The Affiliated Nanping First Hospital of Fujian Medical University, Nanping, China.
Xidi ChiDepartment of Laboratory, The Affiliated Nanping First Hospital of Fujian Medical University, Nanping, China.
Gaofeng ZhangDepartment of Radiology, Affiliated Hospital of Zunyi Medical University, Zunyi City, China. zhanggaofeng7677@163.com.ORCID http://orcid.org/0000-0001-5412-3768
Fujian Medical University · CNZunyi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo assess the prognostic value of coronary computed tomography angiography (CTA) and serum biomarkers for the prediction of major adverse cardiac events (MACE) at three-month and one-year follow-ups. METHODS AND

resultsA total of 720 patients with acute chest pain and normal electrocardiography (ECG) were included in the prospective cohort study. These patients received both coronary CTA screening and serum biomarkers testing, followed by three-month and one-year follow-ups for the occurrence of major adverse cardiac events (MACE). The primary outcome was the occurrence of MACE, which is defined as acute coronary syndrome (ACS), nonfatal MI, and all-cause mortality. The MACE rate was 17.8% (128 cases) and 25.2% (182 cases) at three-months and one-year follow-up. ApoB/apoA1(OR = 7.45, P < 0.001) and the number of atherosclerotic vessels (OR = 2.86, P < 0.001) were independent predictors for MACE at the three-month follow-up, so were apoB/apoA1 (OR = 5.23, P = 0.003), Serum amyloid protein A (SAA, OR = 1.04, P < 0.001) and the number of atherosclerotic vessels (OR = 2.54, P < 0.001) at the one-year follow-up. While apoB/apoA1 suggested its sensitivities of 84% for predicting MACE at three-month follow-ups, the number of atherosclerotic vessels had 81% specificity at one-year follow-up.

conclusionsAmong patients with acute chest pain and normal ECG, apoB/apoA1, SAA and the number of atherosclerotic vessels are the most powerful predictors of MACE at three-month and one-year follow-ups.

Indexed as

Chest PainComputed Tomography AngiographyApolipoproteins BBiomarkersCoronary AngiographyFollow-Up StudiesHumansPredictive Value of TestsProspective StudiesApolipoproteins BBiomarkersCoronary artery diseaseCoronary CT angiography (CTA)Major adverse cardiac events (MACE)Potential biomarkersSerum proteins

Identifiers

PMID36445669
PMCPMC9708748
OpenAlexW4290692460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.