Evidence map›Paper›PMID 36445666›Full record

SynthesisThe international journal of cardiovascular imaging2022

Prognostic value of cardiac magnetic resonance derived global longitudinal strain analysis in patients with ischaemic and non-ischaemic dilated cardiomyopathy: a systematic review and meta-analysis.

Lucas Chun Wah Fong, Nicholas Ho Cheung Lee, Jessica Wai Ling Poon, Calvin W L Chin, Baroc He, Lin Luo, Catherine Chen, Eric Yuk Fai Wan, Dudley J Pennell, Raad Mohiaddin and 1 more

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In one paragraph

Synthesis in The international journal of cardiovascular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Cardiovascular magnetic resonance for therapy monitoring in cardiomyopathies.European heart journal. Imaging methods and practice · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lucas Chun Wah FongDepartment of Diagnostic Radiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital Hong Kong, Hong Kong, China.
Nicholas Ho Cheung LeeDepartment of Diagnostic Radiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital Hong Kong, Hong Kong, China.
Jessica Wai Ling PoonDepartment of Medicine, Ruttonjee and Tang Shiu Kin Hospitals, Hong Kong, China.
Calvin W L ChinDepartment of Cardiology, National Heart Centre Singapore, Singapore, Singapore.
Baroc HeDepartment of Medical Imaging, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Lin LuoDepartment of Medical Imaging, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Catherine ChenDepartment of Medical Imaging, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Eric Yuk Fai WanDepartment of Family Medicine and Primary Care, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Dudley J PennellRoyal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Raad MohiaddinRoyal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Ming-Yen NgDepartment of Diagnostic Radiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital Hong Kong, Hong Kong, China. myng2@hku.hk.ORCID http://orcid.org/0000-0001-9533-3892

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac magnetic resonance (CMR) derived left ventricular global longitudinal strain (LV-GLS) for evaluating dilated cardiomyopathy patients has been addressed in studies with contradictory results. We therefore performed the first systematic review evaluating evidence on the prognostic value of CMR derived LV-GLS for ischaemic (IDCM) and non-ischaemic dilated cardiomyopathy (NDCM) patients. Systematic review (PROSPERO CRD42020171582) identified studies up to January 2021 that measured LV-GLS for predicting major adverse cardiac events among dilated cardiomyopathy patients. Studies were identified from MEDLINE, Embase and PubMed by two independent reviewers. 2099 studies were screened. Three prospective and three retrospective observational studies comprising of 1758 patients (29% IDCM patients; 71% NDCM patients) with a weighted mean follow up of 3 years (SD = 1 year) were identified. All six studies included mortality in the primary composite outcome. LV-GLS was associated with increase primary composite outcome among mild to moderately impaired left ventricular ejection fraction (LVEF) IDCM and NDCM patients (> 30%) in univariable and multivariable analysis. Association was lost among severely impaired LVEF patients (< 30%). From sensitivity analysis, LV-GLS showed significant association with death among NDCM patients (HR 1.27; 95% CI 1.10-1.46; p = 0.001; I

Indexed as

Cardiomyopathy, DilatedHumansMagnetic Resonance SpectroscopyOrganic ChemicalsPredictive Value of TestsPrognosisProspective StudiesRetrospective StudiesStroke VolumeVentricular Function, LeftNocardia delipidated cell mitogenOrganic ChemicalsCardiovascular magnetic resonanceDilated cardiomyopathyGlobal longitudinal strainLate gadolinium enhancementMeta-analysisPrognosis

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.