Evidence map›Paper›PMID 36445659›Full record

ArticleThe international journal of cardiovascular imaging2022

Ventricular-arterial decoupling is associated with in-hospital adverse events in normotensive pulmonary embolism.

Omid Kiamanesh, Graeme Prosperi-Porta, Lea Harper, Kevin Solverson, Paul Boiteau, Doug Helmersen, André Ferland, Nowell Fine, Jason Weatherald

Abstract read
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In one paragraph

Article in The international journal of cardiovascular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Omid Kiamanesh *Division of Cardiology, Department of Cardiac Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Graeme Prosperi-Porta *Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Lea HarperDivision of Respirology, Department of Medicine, University of Calgary, Calgary, AB, Canada.
Kevin SolversonDepartment of Critical Care Medicine, University of Calgary, Calgary, AB, Canada.
Paul BoiteauDepartment of Critical Care Medicine, University of Calgary, Calgary, AB, Canada.
Doug HelmersenDivision of Respirology, Department of Medicine, University of Calgary, Calgary, AB, Canada.
André FerlandDepartment of Critical Care Medicine, University of Calgary, Calgary, AB, Canada.
Nowell FineDivision of Cardiology, Department of Cardiac Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Jason WeatheraldLibin Cardiovascular Institute, University of Calgary, Calgary, AB, Canada. jason.weatherald@albertahealthservices.ca.
University of Calgary · CALibin Cardiovascular Institute of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During acute pulmonary embolism (PE) a compensatory increase in right ventricular (RV) contractility is required to match increased afterload to maintain right ventricular-pulmonary arterial (RV-PA) coupling. The aim of this study was to assess the prognostic utility of RV-PA decoupling in acute PE. We assessed the association between measures of transthoracic echocardiography (TTE)-derived RV-PA coupling including tricuspid annular plane systolic excursion (TAPSE)/right ventricular systolic pressure (RVSP) and right ventricular fractional area change (FAC)/RVSP as well as stroke volume index (SVI)/RVSP (a measure of pulmonary artery capacitance) with adverse PE-related events (in-hospital PE-related mortality or cardiopulmonary decompensation) using logistic regression analysis. In 820 normotensive patients TTE-derived markers of RV-PA coupling were associated with PE-related adverse events. For each 0.1 mm/mmHg decrease in TAPSE/RVSP the odds of an adverse event increased by 2.5-fold [adjusted OR (aOR) 2.49, 95% confidence interval (CI) 1.46-4.24, p = 0.001], for every 0.1%/mmHg decrease in FAC/RVSP the odds of an adverse event increased by 1.4-fold (aOR 1.42, CI 1.09-1.86, p = 0.010), and for every 0.1 mL/mmHg m

Indexed as

Pulmonary EmbolismVentricular Dysfunction, RightBlood PressureHospitalsHumansPredictive Value of TestsPulmonary ArteryPulmonary embolismRight ventricle-pulmonary artery couplingRight ventricular dysfunctionTransthoracic echocardiography

Identifiers

PMID36445659
OpenAlexW4285594088

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.