Evidence map›Paper›PMID 36445588›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Application of a Bacillus subtilis Whole-Cell Biosensor (P

Carolin Martina Kobras, Sali May Morris, Thorsten Mascher, Susanne Gebhard

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Elucidation ofFrontiers in microbiology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Carolin Martina KobrasLife Sciences Department, Milner Centre for Evolution, University of Bath, Bath, UK.
Sali May MorrisLife Sciences Department, Milner Centre for Evolution, University of Bath, Bath, UK.
Thorsten MascherInstitut für Mikrobiologie, Technische Universität Dresden, Dresden, Germany.
Susanne GebhardLife Sciences Department, Milner Centre for Evolution, University of Bath, Bath, UK. s.gebhard@bath.ac.uk.
University of Bath · GBTU Dresden · DEUniversity of Sheffield · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Whole-cell biosensors, based on the visualization of a reporter strain's response to a particular stimulus, are a robust and cost-effective means to monitor defined environmental conditions or the presence of chemical compounds. One specific field in which such biosensors are frequently applied is drug discovery, that is, the screening of large numbers of bacterial or fungal strains for the production of antimicrobial compounds. Here, we describe the application of a luminescence-based Bacillus subtilis biosensor for the discovery of cell wall active substances; this article is an update to our previous chapter published in 2017. The system is based on the well-characterized promoter P

Indexed as

Bacillus subtilisBiosensing TechniquesAnti-Bacterial AgentsCell MembraneCell WallAnti-Bacterial AgentsAntibioticAntimicrobial peptideBioassayCell envelope stressCell wallLipid II cycleLuminescenceReporter geneStress response

Identifiers

PMID36445588
OpenAlexW4310704656

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.