Evidence map›Paper›PMID 36445397›Full record

SynthesisEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2023

Health-related quality of life after severe trauma and available PROMS: an updated review (part I).

Annesimone Lotfalla, Jens Halm, Tim Schepers, Georgios Giannakópoulos

Abstract readSystematic Review
In one paragraph

Synthesis in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Patient-reported outcome measures within European cohorts of severely injured patients: a systematic review and meta-analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Pooled it
  2. Significant other reported outcome measures within European cohorts of severely injured patients: A systematic review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Pooled it
  3. Parameters influencing health-related quality of life after severe trauma: a systematic review (part II).European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Recovery trajectories after a serious injury or illness: a longitudinal evaluation of health-related quality of life in an Australian cohort.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  14. Review
  15. Patient-Reported Mental Health and Quality of Life in Pediatric Adolescent Idiopathic Scoliosis Patients.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025
    Review
  16. The NACA score predicts mortality in polytrauma patients before hospital admission: a registry-based study.Scandinavian journal of trauma, resuscitation and emergency medicine · 2024
    Article
  17. Observational
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Annesimone LotfallaDepartment of Trauma Surgery, Trauma Unit, Amsterdam University Medical Center, Location Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands. a.lotfalla@amsterdamumc.nl.ORCID http://orcid.org/0000-0003-4005-5850
Jens HalmDepartment of Trauma Surgery, Trauma Unit, Amsterdam University Medical Center, Location Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Tim SchepersDepartment of Trauma Surgery, Trauma Unit, Amsterdam University Medical Center, Location Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Georgios GiannakópoulosDepartment of Trauma Surgery, Trauma Unit, Amsterdam University Medical Center, Location Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThroughout the years, a decreasing trend in mortality rate has been demonstrated in patients suffering severe trauma. This increases the relevance of documentation of other outcomes for this population, including patient-reported outcome measures (PROMs), such as health-related quality of life (HRQoL). The aim of this review was to summarize the results of the studies that have been conducted regarding HRQoL in severely injured patients (as defined by the articles' authors). Also, we present the instruments that are used most frequently to assess HRQoL in patients suffering severe trauma.

methodsA literature search was conducted in the Cochrane Library, EMBASE, PubMed, and Web of Science for articles published from inception until the 1st of January 2022. Reference lists of included articles were reviewed as well. Studies were considered eligible when a population of patients with major, multiple or severe injury and/or polytrauma was included, well-defined by means of an ISS-threshold, and the outcome of interest was described in terms of (HR)QoL. A narrative design was chosen for this review.

resultsThe search strategy identified 1583 articles, which were reduced to 113 after application of the eligibility criteria. In total, nineteen instruments were used to assess HRQoL. The SF-36 was used most frequently, followed by the EQ-5D and SF-12. HRQoL in patients with severe trauma was often compared to normative population norms or pre-injury status, and was found to be reduced in both cases, regardless of the tool used to assess this outcome. Some studies demonstrated higher scoring of the patients over time, suggesting improved HRQoL after considerable time after severe trauma.

conclusionHRQoL in severely injured patients is overall reduced, regardless of the instrument used to assess it. The instruments that were used most frequently to assess HRQoL were the SF-36 and EQ-5D. Future research is needed to shed light on the consequences of the reduced HRQoL in this population. We recommend routine assessment and documentation of HRQoL in severely injured patients.

Indexed as

Multiple TraumaQuality of LifeHumansPatient Reported Outcome MeasuresHealth-related quality of lifeInjuriesInstrumentsLiterature reviewMultiple traumaPatient-outcome assessmentPatient-reported outcomesPolytraumaQoL assessment

Identifiers

PMID36445397
PMCPMC10175342

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.