Evidence map›Paper›PMID 36445128›Full record

ArticleAntimicrobial agents and chemotherapy2022

Increased Expression of Efflux Pump

X H Yu, Z H Hao, P L Liu, M M Liu, L L Zhao, X Zhao

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Pyocyanin produced byAntimicrobial agents and chemotherapy · 2026
    Article
  2. Review
  3. Miniprotein inhibitors of thebioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Frontiers in veterinary science · 2025
    Article
  13. Adaptive response ofMicrobiology (Reading, England) · 2024
    Article
  14. Inhibition ofAntibiotics (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

X H YuCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, People's Republic of China.
Z H HaoCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, People's Republic of China.
P L LiuCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, People's Republic of China.
M M LiuCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, People's Republic of China.
L L ZhaoCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, People's Republic of China.
X ZhaoCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, People's Republic of China.ORCID 0000-0002-1078-7332
Northwest A&F University · CNMcGill University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intensively intermittent use of antibiotics promotes the rapid evolution of tolerance, which may lead to resistance acquisition in the following evolutionary trajectory. In addition to directly exporting antibiotics as an instant resistance strategy, efflux pumps are overexpressed in tolerant strains. To investigate how efflux pumps participate in resistance development from tolerance to resistance, we performed

Indexed as

CiprofloxacinDrug Resistance, BacterialStaphylococcus aureusAnti-Bacterial AgentsATP-Binding Cassette, Sub-Family C ProteinsBacterial ProteinsMicrobial Sensitivity TestsAnti-Bacterial AgentsATP-Binding Cassette, Sub-Family C ProteinsBacterial ProteinsCiprofloxacinefflux pumpsresistanceresistance developmentStaphylococcus aureustolerance

Identifiers

PMID36445128
PMCPMC9765010
OpenAlexW4310458997

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.