Evidence map›Paper›PMID 36444944›Full record

ArticlePharmaceutical biology2022

XiaoEr LianHuaQinqGan alleviates viral pneumonia in mice infected by influenza A and respiratory syncytial viruses.

Wenyan Li, Tongtong Li, Chi Zhao, Tao Song, Yao Mi, Zhang Chuangfeng, Yunlong Hou, Zhenhua Jia

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Wenyan LiHebei Yiling Hospital, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Tongtong LiCollege of Integrated Traditional Chinese and Western Medicine, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Chi ZhaoHebei Medical University, Shijiazhuang, Hebei, China.
Tao SongShijiazhuang Yiling Pharmaceutical Co., Ltd, Shijiazhuang, Hebei, China.
Yao MiShijiazhuang Yiling Pharmaceutical Co., Ltd, Shijiazhuang, Hebei, China.
Zhang ChuangfengShijiazhuang Yiling Pharmaceutical Co., Ltd, Shijiazhuang, Hebei, China.
Yunlong HouCollege of Integrated Traditional Chinese and Western Medicine, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.ORCID 0000-0002-6989-8221
Zhenhua JiaCollege of Integrated Traditional Chinese and Western Medicine, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.ORCID 0000-0001-5132-1099
Shijiazhuang Yiling Pharmaceutical (China) · CNHebei University of Chinese Medicine · CNHebei Yiling Hospital · CNHebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextXiaoer lianhuaqinqgan (XELH), developed based on Lianhua Qingwen (LHQW) prescription, contains 13 traditional Chinese medicines. It has completed the investigational new drug application to treat respiratory viral infections in children in China.

objectiveThis study demonstrates the pharmacological effects of XELH against viral pneumonia. MATERIALS AND

methodsThe antiviral and anti-inflammatory effects of XELH were investigated

results

conclusionXELH efficacy partially depends on integrated immunoregulatory effects. XELH is a promising therapeutic option against childhood respiratory viral infections.

Indexed as

Influenza A Virus, H1N1 SubtypeInfluenza A Virus, H9N2 SubtypeInfluenza, HumanPneumonia, ViralAnimalsAnti-Inflammatory AgentsCytokinesHumansInfluenza A Virus, H3N2 SubtypeInfluenza A Virus, H7N3 SubtypeLipopolysaccharidesMiceMice, Inbred BALB CRatsRespiratory Syncytial VirusesXylenesAnti-Inflammatory AgentsCytokinesLipopolysaccharidesXylenesanti-inflammatory effectsantiviral effectsimmunoregulatory effectsXiaoer lianhuaqinggan(XELH)

Identifiers

PMID36444944
PMCPMC9809968
OpenAlexW4310362630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.