Evidence map›Paper›PMID 36444863›Full record

ArticleJournal of the American Heart Association2022

Impact of Diabetes on 10-Year Outcomes Following ST-Segment-Elevation Myocardial Infarction: Insights From the EXAMINATION-EXTEND Trial.

Francesco Spione, Victor Arevalos, Rami Gabani, Luis Ortega-Paz, Josep Gomez-Lara, Victor Jimenez-Diaz, Marcelo Jimenez, Pilar Jiménez-Quevedo, Roberto Diletti, Javier Pineda and 23 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 14 institutions in 5 countries.

Francesco SpioneHospital Clínic, Cardiovascular Clinic Institute Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.ORCID 0000-0002-9327-5286
Victor ArevalosHospital Clínic, Cardiovascular Clinic Institute Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.ORCID 0000-0001-9525-1133
Rami GabaniHospital Clínic, Cardiovascular Clinic Institute Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.ORCID 0000-0002-7729-0953
Luis Ortega-PazHospital Clínic, Cardiovascular Clinic Institute Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.ORCID 0000-0002-9567-3253
Josep Gomez-LaraHospital Universitari de Bellvitge Institut d'Investigació Biomedica de Bellvitge Hospitalet de Llobregat Spain.ORCID 0000-0001-9731-4767
Victor Jimenez-DiazHospital Alvaro Cunqueiro Vigo Spain.ORCID 0000-0002-5271-1993
Marcelo JimenezUniversity Hospital of Sant Pau Barcelona Spain.ORCID 0000-0001-7126-8950
Pilar Jiménez-QuevedoUniversity Hospital San Carlos Madrid Spain.
Roberto DilettiThoraxcenter Rotterdam The Netherlands.ORCID 0000-0002-2344-6705
Javier PinedaHospital General of Alicante Alicante Spain.ORCID 0000-0002-0706-3851
Gianluca CampoCardiology Unit Azienda Ospedaliera Universitaria di Ferrara Cona Italy.ORCID 0000-0002-5150-188X
Antonio SilvestroUniversity Hospital Bolognini Seriate Bergamo Italy.
Jaume MaristanyHospital Son Dureta Palma de Mallorca Spain.
Xacobe FloresHospital Universitario A Coruña Spain.
Loreto OyarzabalHospital Universitari de Bellvitge Institut d'Investigació Biomedica de Bellvitge Hospitalet de Llobregat Spain.ORCID 0000-0002-4090-6646
Guillermo Bastos-FernandezHospital Alvaro Cunqueiro Vigo Spain.ORCID 0000-0002-0882-2573
Andrés IñiguezHospital Alvaro Cunqueiro Vigo Spain.
Antonio SerraUniversity Hospital of Sant Pau Barcelona Spain.ORCID 0000-0003-4641-1879
Javier EscanedUniversity Hospital San Carlos Madrid Spain.ORCID 0000-0003-4932-0112
Alfonso IelasiUniversity Hospital Bolognini Seriate Bergamo Italy.
Maurizio TespiliUniversity Hospital Bolognini Seriate Bergamo Italy.
Mattie LenzenThoraxcenter Rotterdam The Netherlands.
Nieves GonzaloUniversity Hospital San Carlos Madrid Spain.ORCID 0000-0003-3827-945X
Pascual BordesHospital General of Alicante Alicante Spain.
Matteo TebaldiCardiology Unit Azienda Ospedaliera Universitaria di Ferrara Cona Italy.ORCID 0000-0002-2805-8090
Simone BiscagliaCardiology Unit Azienda Ospedaliera Universitaria di Ferrara Cona Italy.ORCID 0000-0001-6074-2370
Soheil Al-ShaibaniThoraxcenter Rotterdam The Netherlands.ORCID 0000-0001-8524-5581
Rafael RomagueraHospital Universitari de Bellvitge Institut d'Investigació Biomedica de Bellvitge Hospitalet de Llobregat Spain.ORCID 0000-0002-6413-3502
Joan Antoni Gomez-HospitalHospital Universitari de Bellvitge Institut d'Investigació Biomedica de Bellvitge Hospitalet de Llobregat Spain.ORCID 0000-0002-3249-3095
Josep Rodes-CabauHospital Clínic, Cardiovascular Clinic Institute Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.ORCID 0000-0001-8237-7095
Patrick W SerruysInternational Center of Circulatory Health Imperial College London London United Kingdom.ORCID 0000-0002-9636-1104
Manel SabatéHospital Clínic, Cardiovascular Clinic Institute Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.ORCID 0000-0002-2316-3705
Salvatore BrugalettaHospital Clínic, Cardiovascular Clinic Institute Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.ORCID 0000-0001-5845-1435
Bellvitge University Hospital · ESAzienda Ospedaliera Bolognini Seriate · ITConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESHospital Clínico San Carlos · ESUniversity Hospital Complex Of Vigo · ESHospital de Sant Pau · ESHospital General Universitario de Alicante Doctor Balmis · ESArcispedale Sant'Anna · ITComplexo Hospitalario Universitario A Coruña · ESHospital Universitario Son Dureta · ESInstituto de Salud Carlos III · ESNational University of Ireland · IEOllscoil na Gaillimhe – University of Galway · IEUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Long-term outcomes of ST-segment-elevation myocardial infarction in patients with diabetes have been barely investigated. The objective of this analysis from the EXAMINATION-EXTEND (10-Years Follow-Up of the EXAMINATION trial) trial was to compare 10-year outcomes of patients with ST-segment-elevation myocardial infarction with and without diabetes. Methods and Results Of the study population, 258 patients had diabetes and 1240 did not. The primary end point was patient-oriented composite end point of all-cause death, any myocardial infarction, or any revascularization. Secondary end points were the individual components of the primary combined end point, cardiac death, target vessel myocardial infarction, target lesion revascularization, and stent thrombosis. All end points were adjusted for potential confounders. At 10 years, patients with diabetes showed a higher incidence of patient-oriented composite end point compared with those without (46.5% versus 33.0%; adjusted hazard ratio [HR], 1.31 [95% CI, 1.05-1.61];

Indexed as

Diabetes MellitusMyocardial InfarctionHumansdiabetesdrug‐eluting stentpercutaneous coronary interventionST‐segment–elevation myocardial infarction

Identifiers

PMID36444863
PMCPMC9851431
OpenAlexW4310240061

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.