ArticleJACC. Asia2022
Prognostic Impact of Systemic Coagulation-Inflammation Index in Acute Type A Aortic Dissection Surgery.
Article in JACC. Asia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04918108 (Inflammatory Response and Anti-inflammatory Action for Aortopathy & Arteriopathy), which is not on this map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Inflammatory Response and Anti-inflammatory Action for Aortopathy & Arteriopathy (5A-Plan): A Multicenter Cohort Study
Who cites it
22 citing papers in PubMed, 33 citations in OpenAlex.
- Relationship Between the Systemic Coagulation-Inflammation Index and Radial Artery Occlusion After Transradial Coronary Angiography.Cardiology research · 2026Article
- Article
- Machine-learning-guided transcriptomic integration identifies GFM1 as a lactylation-related candidate biomarker in aortic dissection.Scientific reports · 2026Article
- Integrating Machine Learning for Early COPD Prediction in Lung Cancer Patients: A Focus on Systemic Coagulation-Inflammation Index.International journal of chronic obstructive pulmonary disease · 2026Article
- Machine Learning-Based Prediction of Lower Extremity Deep Vein Thrombosis in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease.International journal of general medicine · 2026Article
- Preoperative Systemic Coagulation Inflammation Index may be a Predictor of Worse Outcomes After Carotid Endarterectomy.Sisli Etfal Hastanesi tip bulteni · 2026Article
- Thromboelastography and interleukin-6 predict postoperative negative remodeling of descending aorta in patients with type A aortic dissection.Journal of thoracic disease · 2025Article
- A retrospective observational study on the prognostic role of inflammatory markers in futile recanalization after endovascular treatment for large-vessel stroke.The Journal of international medical research · 2025Observational
- Efficacy of hemadsorption combining with cardiopulmonary bypass used in patients with acute type A aortic dissection.Journal of cardiothoracic surgery · 2025Article
- Systematic Review and Meta-analysis of Admission Inflammatory Biomarkers for Evaluating Prognosis in Acute Type A Aortic Dissection.Aorta (Stamford, Conn.) · 2025Article
- Article
- Inflammatory Trajectory and Anti-Inflammatory Pharmacotherapy in Frozen Elephant Trunk-Treated Acute Type I Aortic Dissection.Journal of the Society for Cardiovascular Angiography & Interventions · 2024Article
- A novel nomogram model to predict in-hospital mortality in patients with acute type A aortic dissection after surgery.Journal of cardiothoracic surgery · 2024Article
- Short- and Long-term survival prediction in patients with acute type A aortic dissection undergoing open surgery.Journal of cardiothoracic surgery · 2024Article
- Operative Mortality After Type A Aortic Dissection Surgery: Differences Based on Sex and Age.JACC. Advances · 2024Article
- Anti-inflammatory response-based risk assessment in acute type A aortic dissection: A national multicenter cohort study.International journal of cardiology. Heart & vasculature · 2024Article
- Yes-associated protein-based detection of acute type A aortic dissection and evaluation of therapeutic responses.Frontiers in cardiovascular medicine · 2024Article
- Inflammatory profiles define phenotypes with clinical relevance in acute type A aortic dissection.Journal of cardiovascular translational research · 2023Article
- Inflammatory risk stratification individualizes anti-inflammatory pharmacotherapy for acute type A aortic dissection.Innovation (Cambridge (Mass.)) · 2023Article
- Early-term prognosis in patients with acute aortic dissection: calm before the storm.Revista da Associacao Medica Brasileira (1992) · 2023Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: A novel hematologic parameter, systemic coagulation-inflammation (SCI) index reflecting inflammation and coagulation pathways could be easily obtained from clinically routine laboratory findings. We hypothesize that the SCI index has prognostic implication in predicting operative mortality for patients with acute type A aortic dissection (ATAAD). Objectives: This study aims to investigate the prognostic value of the SCI index and to establish an SCI-adding nomogram for mortality prediction in ATAAD patients. Methods: A total of 1,967 ATAAD patients surgically repaired were collected from 12 Chinese cardiovascular centers by the 5A (Additive Anti-inflammatory Action for Aortopathy & Arteriopathy [Multicenter Retrospective Study]) study III (2016-2020). SCI index was calculated as platelet count × fibrinogen/white blood cell count on admission. By adding SCI index, a nomogram was developed and evaluated for 90-day mortality prediction with conventional predictors via the Cox model with 10-fold cross-validation. Results: Patients were stratified with low SCI (<40), middle SCI (40-100), or high SCI (>100). The 90-day survival rates increased with SCI index (low 86.9%; [95% CI: 84.9%-89.0%], middle 92.7% [95% CI: 90.9%-94.9%], and high 96.4% [95% CI: 94.2%-98.6%]; log-rank Conclusions: SCI index is easily obtainable, performs moderately well as a predictor of short-term mortality in ATAAD patients, and may be useful for risk stratification in emergency settings. (Additive Anti-inflammatory Action for Aortopathy & Arteriopathy [Multicenter Retrospective Study] III NCT04918108).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.