Evidence map›Paper›PMID 36443813›Full record

ArticleBMC rheumatology2022

Rheumatic disease patient decision-making about COVID-19 vaccination: a qualitative analysis.

Yomei P Shaw, Sara Hustek, Nina Nguyen, Makenzie Starlin, Kristin Wipfler, Beth I Wallace, Kaleb Michaud

Open access · goldAbstract read
In one paragraph

Article in BMC rheumatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yomei P ShawFORWARD, The National Databank for Rheumatic Diseases, Wichita, KS, USA.
Sara Hustek *University of Michigan Division of Rheumatology, Ann Arbor, MI, USA.
Nina Nguyen *University of Michigan Division of Rheumatology, Ann Arbor, MI, USA.
Makenzie Starlin *University of Nebraska Medical Center, Omaha, NE, USA.
Kristin WipflerFORWARD, The National Databank for Rheumatic Diseases, Wichita, KS, USA.
Beth I WallaceUniversity of Michigan Division of Rheumatology, Ann Arbor, MI, USA.
Kaleb MichaudFORWARD, The National Databank for Rheumatic Diseases, Wichita, KS, USA. kmichaud@unmc.edu.
University of Michigan–Ann Arbor · USThe National Databank for Rheumatic Diseases · USUniversity of Nebraska Medical Center · US

Funding

CSRD VA IK2 CX002430
6 · The paper itself

Abstract

backgroundAlthough patients with rheumatic and musculoskeletal diseases (RMDs) are at increased risk for adverse outcomes of COVID-19 illness compared to healthy controls, they also have lower rates of willingness to be vaccinated. Previous research has identified reasons for vaccine hesitancy among patients with RMDs (such as concerns about side effects and flares), but little is known about what these reasons mean in the context of patients' lives, or how vaccine decision making is experienced from a patient perspective. Our objective was to describe decision-making about COVID-19 vaccination among RMD patients.

methodsParticipants in a RMD registry were invited to complete monthly online surveys regarding COVID-19 vaccination from March-June 2021. We qualitatively analyzed comments from two open-ended survey questions reporting general experiences with vaccination and side effects. Comments were coded for attitudes towards COVID-19 vaccination, vaccine access, rheumatologic medication management around vaccination, and vaccine side effects. Themes were identified for the process and context of COVID-19 vaccine decisions, patient motivations for receiving or avoiding vaccination, and consistency of peri-vaccine medication management with current ACR guidelines.

resultsWe analyzed 710 comments from 537 respondents. Commenting respondents had a mean age of 64 years, were 87% female, 94% white, and 93% received/intended to receive ≥ 1 dose of a COVID-19 vaccine. Desire for protection and a return to normal routines motivated some commenters to get vaccinated, while concerns about vaccine side effects motivated others to delay or avoid vaccination. Several commenters reported disease flares following vaccination. Some commenters did not consult their providers about vaccination and failed to withhold immunomodulatory medications during vaccination, while others withheld medications more conservatively than recommended by current ACR guidelines, either on their own or directed by their provider.

conclusionsWhile most commenters were vaccine-accepting, challenges to COVID-19 vaccine uptake in the RMD population may include fears of side effects, including worsened RMD symptoms, and perceptions that vaccination is unnecessary. Addressing these concerns and beliefs may be critical for promoting vaccination in this population.

Indexed as

COVID-19Medication adherenceQualitative researchRheumatic diseasesVaccines

Identifiers

PMID36443813
PMCPMC9706890
OpenAlexW4310191024

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.