Evidence map›Paper›PMID 36443691›Full record

ArticleBMC infectious diseases2022

Frequency and functional profile of circulating TCRαβ

Yuting Tan, Shi Zou, Wei Guo, Yanni Xiang, Yu Dong, Qi Zhu, Songjie Wu, Mingqi Luo, Ling Shen, Ke Liang

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Increased CD95Frontiers in immunology · 2026
    Article
  3. Nonspecific increase of αβTCRWorld journal of pediatrics : WJP · 2024
    Observational
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Yuting Tan *Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
Shi Zou *Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
Wei Guo *Wuhan Research Center for Infectious Diseases and Cancer, Chinese Academy of Medical Sciences, Wuhan, China.
Yanni XiangDepartment of Intensive Care Medicine, Yichang Central People's Hospital, Yichang, Hubei, China.
Yu DongDepartment of Geriatrics, Zhongnan Hospital of Wuhan University, Wuhan, China.
Qi ZhuWuhan Pulmonary Hospital, Wuhan Institute for Tuberculosis Control, Wuhan, China.
Songjie WuWuhan Research Center for Infectious Diseases and Cancer, Chinese Academy of Medical Sciences, Wuhan, China.
Mingqi LuoDepartment of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
Ling ShenDepartment of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine, Chicago, IL, USA. lshen@uic.edu.
Ke LiangDepartment of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China. keliang@whu.edu.cn.
Wuhan Center for Disease Control and Prevention · CNWuhan University · CNUniversity of Illinois Chicago · USWuhan Pulmonary Hospital · CNYichang Central People's Hospital · CNZhongnan Hospital of Wuhan University · CN

Funding

Medical Science Advancement Program (Basic Medical Sciences) of Wuhan University TFJC2018004Medical Science and Technology Innovation Platform Support Project of Zhongnan Hospital, Wuhan University PTXM2020008Science and Technology Innovation Cultivation Fund of Zhongnan Hospital, Wuhan University cxpy2017043
6 · The paper itself

Abstract

backgroundIncreased frequency of circulating double negative T (DNT, CD4

methodsA cross-sectional study was conducted to investigate the frequency and functional profiles of peripheral TCRαβ

resultsSignificantly increased frequency of TCRαβ

conclusionsReduced apoptosis may take part in the mechanism of increased frequency of peripheral TCRαβ

Indexed as

CoinfectionHIV InfectionsTuberculosisAnnexin A5CD8-Positive T-LymphocytesCross-Sectional StudiesCytokinesGranzymesHumansReceptors, Antigen, T-Cell, alpha-betaAnnexin A5CytokinesGranzymesReceptors, Antigen, T-Cell, alpha-betaFas, CCR5Granzyme AHuman immunodeficiency virusTCRαβ+ double negative T cellsTuberculosis

Identifiers

PMID36443691
PMCPMC9703676
OpenAlexW4310117569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.