Evidence map›Paper›PMID 36443541›Full record

ArticleInternational ophthalmology2023

Comparison of retinal and choroidal changes in Fuchs' uveitis syndrome.

Ali Safa Balci, Seren Pehlivanoglu, Berna Basarir, Cigdem Altan

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In one paragraph

Article in International ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Ali Safa BalciDepartment of Ophthalmology, Beyoglu Eye Training and Research Hospital, University of Health Sciences Turkey, 34420, Istanbul, Turkey. alisafabalci@gmail.com.ORCID http://orcid.org/0000-0001-9161-7839
Seren PehlivanogluDepartment of Ophthalmology, Beyoglu Eye Training and Research Hospital, University of Health Sciences Turkey, 34420, Istanbul, Turkey.
Berna BasarirDepartment of Ophthalmology, Beyoglu Eye Training and Research Hospital, University of Health Sciences Turkey, 34420, Istanbul, Turkey.
Cigdem AltanDepartment of Ophthalmology, Beyoglu Eye Training and Research Hospital, University of Health Sciences Turkey, 34420, Istanbul, Turkey.
Sağlık Bilimleri Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe assessment of retinal and choroidal changes in eyes with unilateral Fuchs uveitis syndrome (FUS) with the fellow eye and healthy control group.

methodsThirty-nine unilateral FUS patients and 42 healthy control subjects were enrolled. Spectralis domain optical coherence tomography (SD-OCT, Spectralis; Heidelberg Engineering GmbH, Heidelberg, Germany) was used to evaluate retinal and choroidal structures. Retinal and choroidal thicknesses were recorded from OCT images. Choroidal images were binarized to calculate choroidal vascularity index (CVI) with ImageJ 1.52 s (National Institutes of Health, Bethesda, MD, USA) program.

resultsCVI was found to be significantly lower in the FUS group compared to the fellow eyes and healthy control groups (p = 0.039 and p = 0.046, respectively). There was no significant difference in central choroidal thickness in the FUS group compared to the fellow eyes and control groups (p = 0.552 and p = 0.321, respectively). There was no statistically significant difference between the 3 groups in terms of macular thickness in all quadrants (p > 0.05 for all quadrants).

conclusionsAffected eyes tend to decrease in CVI, while there is no difference in retinal and central choroidal thicknesses in patients with FUS compared to eyes of other unaffected eyes and healthy individuals. It may be because the chronic inflammation associated with the disease affects the vascular structure of the choroid.

Indexed as

IridocyclitisRetinaChoroidGermanyHumansTomography, Optical CoherenceCentral choroidal thicknessCentral macular thicknessChoroidal vascularity indexEDI-optical coherence tomographyFuchs’ uveitis syndrome

Identifiers

PMID36443541
OpenAlexW4310458613

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.