Evidence map›Paper›PMID 36443393›Full record

ArticleEuropean journal of clinical nutrition2023

Mediators of dietary diversity score (DDS) on NAFLD in Iranian adults: a structural equation modeling study.

Azam Doustmohammadian, Bahareh Amirkalali, Esmaeel Gholizadeh, Mahmoodreza Khoonsari, Amir Hossein Faraji, Mehdi Nikkhah, Mansooreh Maadi, Nima Motamed, Mohsen Reza Mansourian, Melika Hajjar and 5 more

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Article in European journal of clinical nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Azam DoustmohammadianGastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran.
Bahareh AmirkalaliGastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran.
Esmaeel GholizadehGastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran.
Mahmoodreza KhoonsariGastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran.
Amir Hossein FarajiGastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran.
Mehdi NikkhahGastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran.
Mansooreh MaadiGastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran.
Nima MotamedDepartment of Social Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Mohsen Reza MansourianGastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran.
Melika HajjarStudent Research Committee (National Nutrition and Food Technology Research Institute, Department of Community Nutrition, School of Nutrition Sciences and Food Technology), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Cain C T ClarkCentre for Intelligent Healthcare, Coventry University, Coventry, CV1 5FB, UK.
Samira ChaibakhshEye Reasearch Center, The Five Senses Health Institute, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Fahimeh Safarnezhad TameshkelGastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran.
Arian AfzaliGastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran.
Farhad ZamaniGastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran. zamani.farhad@gmail.com.
Iran University of Medical Sciences · IRCoventry University · GBNational Nutrition and Food Technology Research Institute · IRZanjan University of Medical Sciences · IR

Funding

Iran University of Medical Sciences (IUMS) 99-2-30-19054
6 · The paper itself

Abstract

backgroundThe current study examines the association between the Dietary Diversity Score (DDS) and nonalcoholic fatty liver disease (NAFLD) in Iranian adults using structural equation modeling (SEM).

methodsA sample of 3220 adults from the Amol Cohort Study was recruited for this cross-sectional study. Dietary acid load (DAL) and DDS were calculated using the data obtained from a validated food frequency questionnaire. Anthropometric parameters, blood pressure, biochemical measurements, and liver ultrasonography were evaluated according to standard protocols.

resultsDDS was neither directly nor indirectly associated with a greater prevalence of NAFLD. In the second model (DDS sub-scores model), the association of DAL with NAFLD was fully mediated through waist circumference (WC) (of DAL to WC: β = 0.14, P < 0.0001, and of WC to NAFLD: β = 0.50, P < 0.001). Vegetable and fruit diversity scores had a significant negative indirect relationship with NAFLD prevalence through DAL (β = -0.06, P = 0.001, β = -0.10, P < 0.001, respectively). Meat diversity score was positively associated with NAFLD prevalence in a full mediational process through DAL (β = 0.12, P < 0.001). The SEM fit indices suggested a reasonably adequate fit of the data to the DDS model (Χ2/df = 4.76, GFI = 0.98, AGFI = 0.97, IFI = 0.97, CFI = 0.97, RMSEA = 0.03, and SRMR = 0.02) and its sub-scores model (Χ

conclusionMeat diversity and lack of vegetable and fruit diversity were indirectly associated with NAFLD prevalence through DAL and WC mediators. Interventions for NAFLD may be more successful if they target a lower intake of animal protein sources and dietary diversity, particularly vegetable and fruit diversity.

Indexed as

Non-alcoholic Fatty Liver DiseaseAnimalsCohort StudiesCross-Sectional StudiesDietHumansIranLatent Class AnalysisVegetables

Identifiers

PMID36443393
OpenAlexW4310117715

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.