Evidence map›Paper›PMID 36443155›Full record

ArticleVaccine2023

Persistent drop in confidence following US recommended pause of Ad26.COV2.S vaccine administration.

Benjamin Rader, Molly E Chiang, Douglas L Kriner, Rebecca L Weintraub, John S Brownstein

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Benjamin RaderComputational Epidemiology Lab, Boston Children's Hospital, 401 Park Drive, 7th Floor, Boston, MA 02215, USA; Department of Epidemiology, Boston University School of Public Health, 715 Albany Street, Boston, MA 02118, USA. Electronic address: benjamin.rader@childrens.harvard.edu.
Molly E ChiangComputational Epidemiology Lab, Boston Children's Hospital, 401 Park Drive, 7th Floor, Boston, MA 02215, USA; Department of Human Evolutionary Biology, Harvard University, 11 Divinity Avenue, Cambridge, MA 02138, USA.
Douglas L KrinerDepartment of Government, Cornell University, 214, White Hall, Ithaca, NY 14853, USA.
Rebecca L WeintraubAriadne Labs, Harvard T.H. Chan School of Public Health & Brigham and Women's Hospital, 401 Park Drive, 3rd Floor, Boston, MA 02215, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA.
John S BrownsteinComputational Epidemiology Lab, Boston Children's Hospital, 401 Park Drive, 7th Floor, Boston, MA 02215, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA. Electronic address: john.brownstein@childrens.harvard.edu.
Boston Children's Hospital · USBoston University · USBrigham and Women's Hospital · USCornell University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Janssen COVID-19 vaccine came to market in February 2021 as the first non-mRNA and first single-dose formula approved for use in the US. In April 2021, a temporary pause was recommended for the vaccine after the discovery of rare but serious post-vaccination side-effects. We fielded a large-scale nationally representative survey (n = 401,398) on individual confidence in each of the COVID-19 vaccine formulas available in the US before, during, and after this pause. We find widespread loss of confidence in the Janssen vaccine across gender, age, and other demographics, which persisted over time and after lifting of the halt. Despite this drop, overall reasons for remaining unvaccinated were stable and there was a concurrent minor bump in confidence towards other vaccine formulas. This contrast between the persistent reduction in confidence in the Janssen vaccine and the apparent maintenance of the broader campaign's integrity, highlights the complex dynamics and downstream effects of the pause.

Indexed as

COVID-19Drug-Related Side Effects and Adverse ReactionsAd26COVS1COVID-19 VaccinesHumansVaccinationAd26COVS1COVID-19 VaccinesAdverse eventsJohnson and JohnsonVaccine acceptanceVaccine confidenceVaccine hesitancyVaccine policy

Identifiers

PMID36443155
PMCPMC9692206
OpenAlexW4310061702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.