Evidence map›Paper›PMID 36442959›Full record

ReviewPET clinics2023

Brain PET Imaging: Approach to Cognitive Impairment and Dementia.

Matthew Spano, Michelle Roytman, Mariam Aboian, Babak Saboury, Ana Franceschi, Gloria C Chiang

Erratum issuedOpen access · greenAbstract readReview
In one paragraph

Review in PET clinics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Hybrid PET/MRI in Neurodegenerative Disorders.Advances in clinical radiology · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

Matthew SpanoDepartment of Radiology, Weill Cornell Medicine, NewYork-Presbyterian Hospital, 525 East 68th Street, Starr Pavilion, Box 141, New York, NY 10065, USA.
Michelle RoytmanDepartment of Radiology, Weill Cornell Medicine, NewYork-Presbyterian Hospital, 525 East 68th Street, Starr Pavilion, Box 141, New York, NY 10065, USA.
Mariam AboianDepartment of Radiology, Yale School of Medicine, 330 Cedar Street, New Haven, CT 06520, USA.
Babak SabouryDepartment of Radiology and Imaging Sciences, NIH Clinical Center, 10 Center Dr, Bethesda, MD 20892, USA.
Ana FranceschiDepartment of Radiology, Northwell Health/Donald and Barbara Zucker School of Medicine, Lenox Hill Hospital, 100 East 77th Street, 3rd Floor, New York, NY 10075, USA.
Gloria C ChiangDepartment of Radiology, Weill Cornell Medicine, NewYork-Presbyterian Hospital, 525 East 68th Street, Starr Pavilion, Box 141, New York, NY 10065, USA. Electronic address: gcc9004@med.cornell.edu.
National Institutes of Health Clinical Center · USNew York Hospital Queens · USNewYork–Presbyterian Hospital · USNorthwell Health · USPresbyterian Hospital · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Institutional Career Development CoreKL2TR001862 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$12.2M
The effects of iron on oxidative stress and Alzheimer's biomarkers in amyloid-positive and negative elderly normalR01AG068398 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHIANG, GLORIA CHIA-YI · 2020 to 2024
$2.8M
NCATS NIH HHS KL2 TR001862NCATS NIH HHS UL1 TR001863NIA NIH HHS R01 AG068398
6 · The paper itself

Abstract

Alzheimer disease (AD) is the most common cause of dementia, accounting for 50% to 60% of cases and affecting nearly 6 million people in the United States. Definitive diagnosis requires either antemortem brain biopsy or postmortem autopsy. However, clinical neuroimaging has been playing a greater role in the diagnosis and management of AD, and several PET tracers approach the sensitivity of tissue diagnosis in identifying AD pathologic condition. This review will focus on the utility of PET imaging in the setting of cognitive impairment, with an emphasis on its role in the diagnosis of AD.

Indexed as

Alzheimer DiseaseCognitive DysfunctionBiopsyBrainHumansPositron-Emission TomographyAlzheimer diseaseAmyloidDementiaNeurodegenerationPositron emission tomographyTau

Identifiers

PMID36442959
PMCPMC9713600
OpenAlexW4310018647

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.