Evidence map›Paper›PMID 36442958›Full record

ReviewPET clinics2023

Emerging Role of

Aaron J Sheppard, Sriram S Paravastu, Natalia M Wojnowski, Charles C Osamor, Faraz Farhadi, Michael T Collins, Babak Saboury

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in PET clinics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. American journal of nuclear medicine and molecular imaging · 2026
    Article
  4. [Molecular imaging and biology · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. American journal of nuclear medicine and molecular imaging · 2025
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aaron J SheppardNational Institute of Dental and Craniofacial Research, National Institutes of Health, 30 Convent Drive, Building 30, Room 228, Bethesda, MD 20892-4320, USA.
Sriram S ParavastuNational Institute of Dental and Craniofacial Research, National Institutes of Health, 30 Convent Drive, Building 30, Room 228, Bethesda, MD 20892-4320, USA.
Natalia M WojnowskiNational Institute of Dental and Craniofacial Research, National Institutes of Health, 30 Convent Drive, Building 30, Room 228, Bethesda, MD 20892-4320, USA; Northwestern University Feinberg School of Medicine, 420 East Superior Street, Chicago, IL 60611, USA.
Charles C OsamorNational Institute of Dental and Craniofacial Research, National Institutes of Health, 30 Convent Drive, Building 30, Room 228, Bethesda, MD 20892-4320, USA.
Faraz FarhadiRadiology and Imaging Sciences, Clinical Center, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892-4320, USA; Geisel School of Medicine at Dartmouth, 1 Rope Ferry Road, Hanover, NH 03755, USA.
Michael T CollinsNational Institute of Dental and Craniofacial Research, National Institutes of Health, 30 Convent Drive, Building 30, Room 228, Bethesda, MD 20892-4320, USA.
Babak SabouryRadiology and Imaging Sciences, Clinical Center, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892-4320, USA. Electronic address: babak.saboury@nih.gov.

Funding

Intramural NIH HHS Z99 CL999999
6 · The paper itself

Abstract

Osteoporosis is a metabolic bone disorder that leads to a decline in bone microarchitecture, predisposing individuals to catastrophic fractures. The current standard of care relies on detecting bone structural change; however, these methods largely miss the complex biologic forces that drive these structural changes and response to treatment. This review introduces sodium fluoride (18F-NaF) positron emission tomography/computed tomography (PET/CT) as a powerful tool to quantify bone metabolism. Here, we discuss the methods of 18F-NaF PET/CT, with a special focus on dynamic scans to quantify parameters relevant to bone health, and how these markers are relevant to osteoporosis.

Indexed as

Fractures, BoneOsteoporosisHumansPositron Emission Tomography Computed TomographySodium FluorideTomography, X-Ray ComputedSodium FluorideBone MetabolismBone mineral densityBone TurnoverOsteoporosisSodium fluoride ((18)F-NaF) PET/CT

Identifiers

PMID36442958
PMCPMC9773817

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.