ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2022
Maximizing the impact of limited vaccine supply under different early epidemic conditions: a 2-city modelling analysis of monkeypox virus transmission among men who have sex with men.
Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Dynamics of global mpox epidemics, 1970-2025: a systematic review and meta-analysis of evolving transmissibility and intervention effects.BMJ global health · 2026Pooled it
- Pooled it
- A Review of Epidemiological Modeling Studies on Monkeypox.China CDC weekly · 2026Article
- Public Health Impact of the MVA-BN Vaccine During the 2022 Mpox Outbreak: A Systematic Review.Infectious disease reports · 2025Review
- Cost-effectiveness of vaccination strategies to control future mpox outbreaks in England: a modelling study.The Lancet regional health. Europe · 2025Article
- An evaluation of the preprints produced at the beginning of the 2022 mpox public health emergency.Research integrity and peer review · 2024Article
- Impact of vaccination and high-risk group awareness on the mpox epidemic in the United States, 2022-2023: a modelling study.EClinicalMedicine · 2024Article
- Assessment of Knowledge and Concern of People Living with HIV Regarding Human Mpox and Vaccination.Current HIV research · 2024Article
- A survey-based assessment of rates and covariates of mpox diagnosis and vaccination provides evidence to refine eligibility criteria for mpox vaccination among gay, bisexual and other men who have sex with men in the Netherlands.Frontiers in public health · 2024Article
- Preventing and fighting stigma: a lesson from the first Mpox in Veneto region of Northeast Italy-A case report.Frontiers in public health · 2023Article
- Modeling vaccination and control strategies for outbreaks of monkeypox at gatherings.Frontiers in public health · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe current global monkeypox virus (MPXV) outbreak has disproportionately affected gay, bisexual and other men who have sex with men (GBMSM). Given that many jurisdictions have been faced with limited supplies of MPXV vaccine, we aimed to explore optimal vaccine allocation between 2 linked GBMSM transmission networks over a short-term time horizon, across several epidemic conditions.
methodsWe constructed a deterministic compartmental MPXV transmission model. We parameterized the model to reflect 2 representative, partially connected GBMSM sexual networks ( cities), using 2022 data from Ontario. We simulated a roll-out of 5000 vaccine doses over 30 days that started 45 days after epidemic seeding with 10 imported cases. Within this model, we varied the relative city (network) sizes, epidemic potentials (
resultsUnder our modelling assumptions, we found that a limited MPXV vaccine supply could generally avert more early infections when prioritized to networks that were larger, had more initial infections or had greater
interpretationIn the context of the current global MPXV outbreak, we showed that prioritization of a limited supply of vaccines based on network-level factors can help maximize infections averted during an emerging epidemic. Such prioritization should be grounded in an understanding of context-specific risk drivers and should acknowledge potential connectedness of multiple transmission networks.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.