Evidence map›Paper›PMID 36442516›Full record

ArticleCanadian journal of ophthalmology. Journal canadien d'ophtalmologie2024

Multifocal electroretinographic findings in angiographic macular leakage in the setting of intermediate, posterior, or panuveitis.

Hashem Ghoraba, Jaclyn Hwang, Irmak Karaca, Hassan Khojasteh, Christopher Or, Jonathan Regenold, Moosa Zaidi, Negin Yavari, Ngoc Trong Tuong Than, Sung Who Park and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 78% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Hashem GhorabaSpencer Center for Vision Research, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA.
Jaclyn HwangSpencer Center for Vision Research, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA.
Irmak KaracaSpencer Center for Vision Research, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA.
Hassan KhojastehSpencer Center for Vision Research, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA.
Christopher OrSpencer Center for Vision Research, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA.
Jonathan RegenoldSpencer Center for Vision Research, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA.
Moosa ZaidiSpencer Center for Vision Research, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA.
Negin YavariSpencer Center for Vision Research, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA.
Ngoc Trong Tuong ThanSpencer Center for Vision Research, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA.
Sung Who ParkSpencer Center for Vision Research, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA.
Cigdem YasarSpencer Center for Vision Research, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA.
Amir AkhavanrezayatSpencer Center for Vision Research, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA.
Quan Dong NguyenSpencer Center for Vision Research, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA.. Electronic address: ndquan@stanford.edu.
Vision Eye Institute · AUStanford University · US

Funding

Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI Jeffrey L Goldberg · 2017 to 2026
$8.0M
NEI NIH HHS P30 EY026877
6 · The paper itself

Abstract

objectiveTo evaluate the functional implications of angiographic macular leakage without the presence of intraretinal fluid on optical coherence tomography (OCT) in eyes with intermediate, posterior, or panuveitis.

methodsRetrospective study on patients with a diagnosis of intermediate, posterior, or panuveitis. Patients who had fluorescein angiography, OCT, and multifocal electroretinography (mfERG) within a predetermined time frame were included. Demographic and clinical data including types of ocular inflammation and best-corrected visual acuity (BCVA), in addition to OCT, fluorescein angiography, and mfERG data were collected. The study cohort was divided into 2 groups based on the presence of angiographic macular leakage and macular edema (ME): group 1 (no ME and no macular leakage) and group 2 (presence of macular leakage without ME).

resultsA total of 29 patients (43 eyes) were included in the study, with 13 patients (17 eyes) in group 1 and 16 patients (26 eyes) in group 2. No statistically significant differences in age, sex, anterior-chamber cells, lens status, vitreous cells, vitreous haze, BCVA, or mean central subfoveal thickness were found between groups 1 and 2. All mfERG values, including N

conclusionsIn absence of ME, angiographic macular leakage in eyes with uveitis might not be associated with worse macular function when compared with eyes without angiographic macular leakage.

Indexed as

Macular EdemaPanuveitisElectroretinographyFluorescein AngiographyHumansRetinaRetrospective StudiesTomography, Optical Coherence

Identifiers

PMID36442516
PMCPMC10863997
OpenAlexW4310068423

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.