ArticleJournal of the National Cancer Institute2023
Association between imaging surveillance frequency and outcomes following surgical treatment of early-stage lung cancer.
Article in Journal of the National Cancer Institute, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Dropout after Neoadjuvant Chemoimmunotherapy for Non-Small Cell Lung Cancer in the Veterans Health Administration.The Annals of thoracic surgery · 2026Article
- Adherence to Postoperative Survivorship Quality Metrics in Early-Stage Non-Small Cell Lung Cancer.The Annals of thoracic surgery · 2026Article
- Disruption of Radiological Surveillance Following a Global Health Crisis in Resected Lung Cancer.Thoracic cancer · 2026Observational
- A Vision Toward Risk-Stratified Postoperative Surveillance for Lung Cancer: Harnessing CT and AI.Journal of the American College of Radiology : JACR · 2025Article
- Availability of multidisciplinary treatment modalities and outcomes among patients with resected early-stage non-small cell lung cancer.JNCI cancer spectrum · 2025Article
- Adherence to Posttreatment Surveillance Guidelines in Non-Small Cell Lung Cancer: Retrospective Cohort Study.JMIR cancer · 2025Article
- Article
- The clinical effect of thoracoscopic segmentectomy in the treatment of lung malignancies less than 2CM in diameter.Journal of cardiothoracic surgery · 2024Article
- Impact of radiological follow-up frequency on resected lung cancer: a propensity score matching analysis.Journal of thoracic disease · 2024Article
- Lobe-specific lymph node sampling is associated with lower risk of cancer recurrence.JTCVS open · 2024Article
- [Questions and Answers in Lung Cancer].Open respiratory archivesArticle
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundRecent studies have suggested that more frequent postoperative surveillance imaging via computed tomography following lung cancer resection may not improve outcomes. We sought to validate these findings using a uniquely compiled dataset from the Veterans Health Administration, the largest integrated health-care system in the United States.
methodsWe performed a retrospective cohort study of veterans with pathologic stage I non-small cell lung cancer receiving surgery (2006-2016). We assessed the relationship between surveillance frequency (chest computed tomography scans within 2 years after surgery) and recurrence-free survival and overall survival.
resultsAmong 6171 patients, 3047 (49.4%) and 3124 (50.6%) underwent low-frequency (<2 scans per year; every 6-12 months) and high-frequency (≥2 scans per year; every 3-6 months) surveillance, respectively. Factors associated with high-frequency surveillance included being a former smoker (vs current; adjusted odds ratio [aOR] = 1.18, 95% confidence interval [CI] = 1.05 to 1.33), receiving a wedge resection (vs lobectomy; aOR = 1.21, 95% CI = 1.05 to 1.39), and having follow-up with an oncologist (aOR = 1.58, 95% CI = 1.42 to 1.77), whereas African American race was associated with low-frequency surveillance (vs White race; aOR = 0.64, 95% CI = 0.54 to 0.75). With a median (interquartile range) follow-up of 7.3 (3.4-12.5) years, recurrence was detected in 1360 (22.0%) patients. High-frequency surveillance was not associated with longer recurrence-free survival (adjusted hazard ratio = 0.93, 95% CI = 0.83 to 1.04, P = .22) or overall survival (adjusted hazard ratio = 1.04, 95% CI = 0.96 to 1.12, P = .35).
conclusionsWe found that high-frequency surveillance does not improve outcomes in surgically treated stage I non-small cell lung cancer. Future lung cancer treatment guidelines should consider less frequent surveillance imaging in patients with stage I disease.
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