Evidence map›Paper›PMID 36442431›Full record

ArticleJournal of biomechanics2022

Plantar flexor deficits following Achilles tendon rupture: A novel small animal dynamometer and detailed instructions.

My M Tang, Courtney A Nuss, Natalie Fogarty, Josh R Baxter

Open access · greenAbstract read
In one paragraph

Article in Journal of biomechanics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Achilles Tendon Surgical Repair Partially Restores Early Plantar Flexor Structure and Function in a Rat Model.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
    Article
  2. Learning on a Limb: An outreach module to engage high school students in orthopaedics.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

My M TangDepartment of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, USA.
Courtney A NussDepartment of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, USA.
Natalie FogartyDepartment of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, USA.
Josh R BaxterDepartment of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: josh.baxter@pennmedicine.upenn.edu.
University of Pennsylvania · US

Funding

Overall: Resource-based Center for Musculoskeletal Disorders Research (Overall Application)P30AR069619 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI LOUIS J SOSLOWSKY · 2016 to 2026
$9.1M
Modifying muscle remodeling following Achilles tendon rupturesK01AR075877 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI BAXTER, JOSH · 2020 to 2024
$609k
NIAMS NIH HHS K01 AR075877NIAMS NIH HHS P30 AR069619
6 · The paper itself

Abstract

Plantar flexor functional deficits measured using joint dynamometry are associated with poor outcomes in patients following Achilles tendon rupture. In this study, we developed a small animal dynamometer to quantify functional deficits in a rat Achilles tendon rupture model. Like our reported plantar flexor deficits in patients recovering from Achilles tendon ruptures, we found in our small animal model functional deficits across the ankle range of motion, resulting in an average 34% less positive work being done compared to the uninjured contralateral limb. These functional deficits are similar to 38% less plantar flexor work done by patients who were treated non-surgically in our prior research. Further, these torque deficits were greater in plantar flexion than dorsiflexion, which agree with clinical complaints of limited function during tasks like jumping and hiking. These findings serve as compelling evidence that our Sprague Dawley rat model of an Achilles tendon rupture recapitulates the functional deficits we observed in patients treated nonsurgically. We provide thorough documentation for other groups to build their own dynamometers, which can be modified to meet unique experimental criteria.

Indexed as

Achilles TendonAnimalsRatsRats, Sprague-DawleyTearsDynamometryFunctionOrthopaedic surgeryPreclinical modelRatRehabilitation

Identifiers

PMID36442431
PMCPMC9813868
OpenAlexW4309768781

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.