ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2023
Neuromodulatory effects of transcranial electrical stimulation on emotion regulation in internalizing psychopathologies.
Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Transcranial alternating current stimulation for neuropsychiatric disorders: a systematic review of treatment parameters and outcomes.Frontiers in psychiatry · 2024Pooled it
- Potential Delayed Positive Effects of tDCS on Improving Introspective Accuracy in Social Cognition in Schizophrenia.Schizophrenia bulletin · 2025Trial
- Efficacy and Safety of Transcranial Alternating Current Stimulation Compared to Transcranial Direct Current Stimulation in the Treatment of Psychiatric & Neurological Disorders: A Systematic Review of Head-to-head Trials.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2026Review
- Mechanisms and clinical applications of transcranial alternating current stimulation in the treatment of neuropsychiatric disorders: Current evidence and future directions.Chinese medical journal · 2026Review
- Neurophysiological Markers of Regulation Success in Everyday Life in Depression.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Sex differences in the effects of 10 Hz and 40 Hz transcranial alternating current stimulation on spatial cognition in mice.Biology of sex differences · 2025Article
- The role of the somatosensory system in the feeling of emotions: a neurostimulation study.Social cognitive and affective neuroscience · 2024Article
- A bibliometric analysis of transcranial alternating current stimulation.Frontiers in neuroscience · 2024Article
- Transcranial alternating current stimulation for the treatment of major depressive disorder: from basic mechanisms toward clinical applications.Frontiers in human neuroscience · 2023Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
objectiveWe hypothesize offset theta-tACS (transcranial alternating current stimulation) improves emotion regulation (ER) and psychopathology more than transcranial direct current stimulation (tDCS) in participants with internalizing psychopathologies (IPs).
methodsThis pilot study utilized a double-blind, pseudo-counterbalanced, sham-controlled design with participants with IPs. Participants were assigned to receive tDCS or tACS, underwent four stimulation sessions (two sham), and completed an emotion regulation task (ERT) during or after stimulation. Participants completed the Beck Depression Inventory before/after the study, the Spielberger State and Trait Anxiety Index after each ERT, and rated their arousal, valence, and perceived reappraisal ability during the ERT.
resultsParticipants receiving either stimulation type showed a reduction in anxiety, depression, and valence and arousal ratings. We additionally discovered an effect demonstrating those who received sham stimulation first displayed little-to-no change in any score across the study, but tACS participants who received verum stimulation first showed significant improvements in each metric.
conclusionsImproving ER capabilities via theta tACS has the potential to yield beneficial clinical effects. SIGNIFICANCE: This study adds validity to the use of non-invasive neuromodulatory methods, especially tACS, to alleviate IPs. Additional research is needed to better understand the effects of sham stimulation. Careful consideration of sham incorporation should be made in future studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.