Evidence map›Paper›PMID 36442147›Full record

Observational studyAnnals of the American Thoracic Society2023

Airway Disease in Children with Primary Ciliary Dyskinesia: Impact of Ciliary Ultrastructure Defect and Genotype.

BreAnna Kinghorn, Margaret Rosenfeld, Erin Sullivan, Frankline Onchiri, Thomas W Ferkol, Scott D Sagel, Sharon D Dell, Carlos Milla, Adam J Shapiro, Kelli M Sullivan and 8 more

Open access · greenAbstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Annals of the American Thoracic Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Nutrition and growth of primary ciliary dyskinesia patients: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Advances in respiratory medicine · 2025
    Article
  6. Observational
  7. Article
  8. Article
  9. Observational
  10. Observational
  11. Recognizing clinical features of primary ciliary dyskinesia in the perinatal period.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Review
  12. Ciliary Function, Antigen Stasis and Asthma.International journal of molecular sciences · 2024
    Review
  13. Article
  14. Development and Initial Characterization of Pigs withbioRxiv : the preprint server for biology · 2024
    Article
  15. Article
  16. Article
  17. Review
  18. Primary Ciliary Dyskinesia.Pediatrics · 2024
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 3 countries.

BreAnna KinghornDepartment of Pediatrics, University of Washington School of Medicine, Seattle, Washington.ORCID 0000-0002-3522-5387
Margaret RosenfeldDepartment of Pediatrics, University of Washington School of Medicine, Seattle, Washington.
Erin SullivanDepartment of Pediatrics, University of Washington School of Medicine, Seattle, Washington.
Frankline OnchiriDepartment of Pediatrics, University of Washington School of Medicine, Seattle, Washington.
Thomas W FerkolDepartment of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
Scott D SagelDepartment of Pediatrics, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado.ORCID 0000-0001-6172-4465
Sharon D DellDepartment of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0003-2169-9407
Carlos MillaDepartment of Pediatrics, Stanford University, Palo Alto, California.
Adam J ShapiroDepartment of Pediatrics, McGill University Health Centre Research Institute, Montreal, Quebec, Canada.ORCID 0000-0001-6066-6750
Kelli M SullivanPulmonary Medicine Division.
Maimoona A ZariwalaDepartment of Pathology and Laboratory Medicine, Marsico Lung Institute, and.
Jessica E PittmanDepartment of Pediatrics, Washington University School of Medicine, St. Louis, Missouri; and.
Federico MollicaDepartment of Pediatric Pulmonology and Allergology, Sophia Children's Hospital, and.
Harm A W M TiddensDepartment of Pediatric Pulmonology and Allergology, Sophia Children's Hospital, and.
Mariette Kemner-van de CorputDepartment of Pediatric Pulmonology and Allergology, Sophia Children's Hospital, and.
Michael R KnowlesPulmonary Medicine Division.
Stephanie D DavisDepartment of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
Margaret W LeighDepartment of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
Seattle Children's Hospital · USErasmus MC · NLUniversity of North Carolina at Chapel Hill · USPulmonary Associates · USChildren's Hospital Colorado · USLung Institute · USMcGill University Health Centre · CAStanford University · USUniversity of British Columbia · CAWashington University in St. Louis · US

Funding

The Impact of COVID-19 on People Living with Rare Diseases and Their FamiliesU2CTR002818 · NCATS · CINCINNATI CHILDRENS HOSP MED CTR · PI Maurizio Macaluso, Michael Wagner · 2019 to 2026
$51.2M
NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Longitudinal Characterization of Respiratory Tract Exacerbations and Treatment Responses in Primary Ciliary DyskinesiaU54HL096458 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVIS, STEPHANIE DUGGINS, FERKOL, THOMAS W · 2009 to 2023
$20.0M
Yale Center for Mendelian GenomicsUM1HG006504 · NHGRI · YALE UNIVERSITY · PI GERSTEIN, MARK BENDER, GUNEL, MURAT · 2016 to 2020
$14.8M
Pathogenesis of PCD Lung DiseaseR01HL071798 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KNOWLES, MICHAEL R · 2004 to 2021
$7.2M
NCATS NIH HHS U2C TR002818NCATS NIH HHS UL1 TR002535NHGRI NIH HHS UM1 HG006504NHLBI NIH HHS R01 HL071798NHLBI NIH HHS U54 HL096458
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Ciliary Motility DisordersKartagener SyndromeRespiration DisordersChildCiliaCross-Sectional StudiesDyneinsGenotypeHumansProspective StudiesDyneinsbronchiectasiscomputed tomographylung functionPCDpediatric lung disease

Identifiers

PMID36442147
PMCPMC10112400
OpenAlexW4310458813

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.