Evidence map›Paper›PMID 36442127›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Deletion of

Hui-Young Lee, Hye Rim Jang, Hui Li, Varman T Samuel, Karrie D Dudek, Anna B Osipovich, Mark A Magnuson, Jeffrey Sklar, Gerald I Shulman

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. AGPAT3 deficiency impairs adipocyte differentiation and leads to a lean phenotype in mice.American journal of physiology. Endocrinology and metabolism · 2024
    Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Hui-Young LeeLaboratory of Mitochondria and Metabolic Diseases, School of Medicine, Gachon University, Incheon 21999, Korea.ORCID 0000-0002-3464-6382
Hye Rim JangLaboratory of Mitochondria and Metabolic Diseases, School of Medicine, Gachon University, Incheon 21999, Korea.
Hui LiDepartment of Pathology, University of Virginia, Charlottesville, VA 22908.ORCID 0000-0002-7879-1792
Varman T SamuelDepartment of Internal Medicine, Yale School of Medicine, New Haven, CT 06510.
Karrie D DudekDepartment of Cell and Developmental Biology, Vanderbilt University, Nashville TN 37232.
Anna B OsipovichDepartment of Molecular Physiology and Biophysics, Vanderbilt UniversityNashville, TN 37232.
Mark A MagnusonDepartment of Molecular Physiology and Biophysics, Vanderbilt UniversityNashville, TN 37232.
Jeffrey SklarDepartment of Pathology, Yale School of Medicine, New Haven CT 06510.
Gerald I ShulmanDepartment of Internal Medicine, Yale School of Medicine, New Haven, CT 06510.ORCID 0000-0003-1529-5668
Vanderbilt University · USYale University · USGachon University · KRUniversity of Virginia · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Diabetes Research CenterP30DK045735 · NIDDK · YALE UNIVERSITY · PI Kevan C Herold, GERALD I SHULMAN · 1993 to 2026
$44.0M
Effects of Hepatic Acetyl-CoA Carboxylase Inhibition on NAFLD and Hepatic Insulin ResistanceR01DK113984 · NIDDK · YALE UNIVERSITY · PI SHULMAN, GERALD I · 2017 to 2021
$3.7M
Development of Controlled Release Mitochondrial Protonophore (CRMP) as a Novel Treatment for Type-2 Diabetes and Non-Alcoholic Steatohepatitis in Dysmetabolic Non-Human PrimatesR01DK119968 · NIDDK · YALE UNIVERSITY · PI SHULMAN, GERALD I · 2019 to 2024
$2.7M
Glucagon Regulation of Hepatic Mitochondrial Activity and Glucose Metabolism by InsP3R-1R01DK116774 · NIDDK · YALE UNIVERSITY · PI SHULMAN, GERALD I · 2018 to 2021
$1.7M
The JAZF1 Gene and Type 2 DiabetesR01DK085087 · NIDDK · YALE UNIVERSITY · PI SKLAR, JEFFREY · 2009 to 2011
$1.1M
BLRD VA I01 BX000901NCATS NIH HHS UL1 TR001863NIDDK NIH HHS P30 DK045735NIDDK NIH HHS R01 DK085087NIDDK NIH HHS R01 DK113984NIDDK NIH HHS R01 DK116774NIDDK NIH HHS R01 DK119968
6 · The paper itself

Abstract

Single-nucleotide polymorphisms in the human juxtaposed with another zinc finger protein 1 (

Indexed as

Diabetes Mellitus, Type 2Insulin ResistanceAnimalsCo-Repressor ProteinsDNA-Binding ProteinsGenome-Wide Association StudyGrowth DisordersHepatocyte Nuclear Factor 4HumansInsulin-Like Growth Factor IMiceMice, KnockoutCo-Repressor ProteinsDNA-Binding ProteinsHepatocyte Nuclear Factor 4Insulin-Like Growth Factor IJAZF1 protein, humanJAZF1 protein, mouseheighthnf4ainsulin like growth factor 1jazf1type 2 diabetes

Identifiers

PMID36442127
PMCPMC9894197
OpenAlexW4310102486

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.