Evidence map›Paper›PMID 36442077›Full record

ReviewACS applied materials & interfaces2023

Iron Oxide Nanoparticles Decorated with Functional Peptides for a Targeted siRNA Delivery to Glioma Cells.

Seokhwan Chung, Yutaro Sugimoto, Jianxi Huang, Miqin Zhang

Open access · greenAbstract readReview
In one paragraph

Review in ACS applied materials & interfaces, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 41 citations in OpenAlex.

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  18. Peptide cargo administration: current state and applications.Applied microbiology and biotechnology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Seokhwan Chung
Yutaro Sugimoto
Jianxi Huang
University of Washington · US

Funding

Iron oxide nanotheranostics for breast cancerR01EB026890 · NIBIB · UNIVERSITY OF WASHINGTON · PI ZHANG, MIQIN · 2018 to 2021
$1.9M
NIBIB NIH HHS R01 EB026890
6 · The paper itself

Abstract

Glioma is a deadly form of brain cancer, and the difficulty of treating glioma is exacerbated by the chemotherapeutic resistance developed in the tumor cells over the time of treatment. siRNA can be used to silence the gene responsible for the increased resistance, and sensitize the glioma cells to drugs. Here, iron oxide nanoparticles functionalized with peptides (NP-CTX-R

Indexed as

Brain NeoplasmsGliomaAntineoplastic Agents, AlkylatingCell Line, TumorDacarbazineDrug Resistance, NeoplasmHumansMagnetic Iron Oxide NanoparticlesO(6)-Methylguanine-DNA MethyltransferasePeptidesPolyethylene GlycolsRNA, Small InterferingTemozolomideAntineoplastic Agents, AlkylatingDacarbazineO(6)-Methylguanine-DNA MethyltransferasePeptidesPolyethylene Glycolspolyoxyethylene(10)nonylphenyl etherRNA, Small InterferingTemozolomidecell-penetrating peptidechlorotoxinfunctional peptidegliomairon oxide nanoparticlesiRNA

Identifiers

PMID36442077
PMCPMC11495154
OpenAlexW4310102541

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.