Evidence map›Paper›PMID 36441715›Full record

Trial reportOncotarget2022

Association of fall rate and functional status by

Gwendolyn J McGinnis, Sarah Holden, Betty Yu, Charlton Ransom, Carolyn Guidarelli, Brian De, Kevin Diao, David Boyce, Charles R Thomas, Kerri Winters-Stone and 1 more

Registry-linked trialOpen access · diamondAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Oncotarget, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01635413 (Group Exercise Training for Functional Improvement After Treatment), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01635413 nacompletednot on this map

Group Exercise Training for Functional Improvement After Treatment (The GET FIT Trial)

TypeinterventionalSponsorOHSU Knight Cancer InstituteRan2012 to 2016Enrolled444ConditionsMalignant Neoplasm, PostmenopausalArmsExercise Intervention, Questionnaire Administration
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Gwendolyn J McGinnisDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Sarah HoldenDepartment of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA.
Betty YuDepartment of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA.
Charlton RansomDepartment of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA.
Carolyn GuidarelliSchool of Nursing, Oregon Health and Science University, Portland, OR 97239, USA.
Brian DeDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Kevin DiaoDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
David BoyceDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Charles R ThomasDepartment of Radiation Medicine, Oregon Health and Science University, Portland, OR 97239, USA.
Kerri Winters-StoneSchool of Nursing, Oregon Health and Science University, Portland, OR 97239, USA.
Jacob RaberDepartment of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA.
Oregon Health & Science University · USThe University of Texas MD Anderson Cancer Center · USOregon National Primate Research Center · US

Funding

Oregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)UL1TR002369 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia D Morris, Christopher G. Slatore · 2017 to 2026
$78.4M
OREGON CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024140 · NCRR · OREGON HEALTH & SCIENCE UNIVERSITY · PI ORWOLL, ERIC S. · 2006 to 2011
$61.1M
Effects of apoE Isoform, Sex and Diet on Insulin Regulation in BrainRF1AG059088 · NIA · SEATTLE INST FOR BIOMEDICAL/CLINICAL RES · PI BANKS, WILLIAM A, RABER, JACOB · 2018 to 2020
$2.5M
Hyaluron as a regulator of chemotherapy-induced changes in neurogenesisR21CA223461 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI SHERMAN, LARRY S. · 2019 to 2021
$590k
NCATS NIH HHS UL1 TR002369NCI NIH HHS R21 CA223461NCRR NIH HHS UL1 RR024140NIA NIH HHS RF1 AG059088
6 · The paper itself

Abstract

PURPOSE/

objectivesCancer treatment survivors often report impaired functioning and increased falls. Not all survivors experience the same symptom burden, suggesting individual susceptibilities. MATERIALS AND

methodsData from a subsample of a study of fall prevention exercise in post-treatment female cancer survivors aged 50-75 years old (https://clinicaltrials.gov NCT01635413) were used to conduct a secondary data analysis. ApoE genotype was determined by serum sampling. Physical functioning, frequency of falls, and symptom burden were assessed using survey instruments.

resultsData from 126 female cancer survivors a median of 49 months out from cancer diagnosis were analyzed. ApoE4 carriers trended toward a higher fall rate at baseline (

conclusions

Indexed as

Cancer SurvivorsDrug-Related Side Effects and Adverse ReactionsNeoplasmsAccidental FallsAgedApolipoproteins EExercise TherapyFemaleFunctional StatusGenotypeHumansMiddle AgedApolipoproteins EapoEbreast cancerexercise interventionfall ratefunctional status

Identifiers

PMID36441715
PMCPMC11623406
OpenAlexW4309180703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.