Evidence map›Paper›PMID 36441638›Full record

ArticleJournal of viral hepatitis2023

Evaluation of a pilot emergency department linkage to care program for patients previously diagnosed with Hepatitis C.

Zak Hyde, Raúl Roura, Danielle Signer, Anuj Patel, Jacob Cohen, Mustapha Saheed, Sherilyn Brinkley, Risha Irvin, Mark S Sulkowski, David L Thomas and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of viral hepatitis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Implementation of Universal Hepatitis C Virus Screening in a Tertiary Cancer Center.Journal of the National Comprehensive Cancer Network : JNCCN · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Zak HydeDepartment of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Raúl RouraDepartment of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Danielle SignerDepartment of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Anuj PatelDepartment of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Jacob CohenDepartment of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Mustapha SaheedDepartment of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Sherilyn BrinkleyDivision Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Risha IrvinDivision Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0001-5953-9316
Mark S SulkowskiDivision Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-2145-6352
David L ThomasDivision Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Richard E RothmanDepartment of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Yu-Hsiang HsiehDepartment of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-1616-8014
Johns Hopkins University · US

Funding

Elimination of HCV and related liver disease among HIV-infected and -uninfected people who inject drugsR01DA048063 · NIDA · JOHNS HOPKINS UNIVERSITY · PI Shruti H Mehta, David L Thomas · 2019 to 2026
$4.2M
Patient Oriented Research in Hepatitis C-infected Injection Drug UsersK24DA034621 · NIDA · JOHNS HOPKINS UNIVERSITY · PI SULKOWSKI, MARK SEBASTIAN · 2012 to 2022
$1.2M
NIDA NIH HHS K24 DA034621NIDA NIH HHS R01 DA048063
6 · The paper itself

Abstract

There is a significant number of Emergency Department (ED) patients with known chronic hepatitis C virus (HCV) infection who have not been treated with directly acting antivirals. We implemented a pilot ED-based linkage-to-care program to address this need and evaluated the impact of the program using the HCV Care Continuum metrics. Between March 2015 and May 2016, dedicated patient care navigators identified HCV RNA-positive patients in an urban ED and offered expedited appointments with the on-site viral hepatitis clinic. Patient demographics and care continuum outcomes were abstracted from the EMR and analysed to determine significant factors influencing linkage-to-care (LTC) and treatment initiation rates. The ED linkage-to-care program achieved a 43% linkage-to-care rate (165/384), 22% treatment rate (84/384) and 16% sustained virologic response rate (63/384). Significant associations were found between linkage-to-care and increasing age (OR = 1.03), Medicare insurance (OR = 2.21) and having a primary care physician (PCP) (OR = 4.03). For patients who were linked, the odds of initiating treatment were also positively significantly associated with increasing age (OR = 1.04) and having a PCP (OR = 2.77). For patients who initiated treatment, the odds of sustained virologic response were marginally associated with having a PCP (OR = 4.92).Our ED linkage-to-care program utilized care coordination to successfully link nearly half of approached HCV RNA-positive patients to care. This design can be feasibly replicated by other EDs given limited non-clinical training required for linkage-to-care staff. Adoption of similar programs in other EDs may improve the rates of LTC and treatment initiation for previously diagnosed HCV patients.

Indexed as

Hepatitis CHepatitis C, ChronicAgedEmergency Service, HospitalHepacivirusHumansMass ScreeningMedicareRNAUnited StatesRNAcontinuity of patient careemergency departmentHepatitis Clinkage to carepilot project

Identifiers

PMID36441638
PMCPMC9852079
OpenAlexW4310120316

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.