Evidence map›Paper›PMID 36441629›Full record

ArticleAnimal biotechnology2023

Genome-wide association study for wattles trait in the dairy goat breed.

Xiaolong Xu, Yingwei Guo, Miaoyu Li, Quyu Duan, Fu Li, Jintao Wang, Nan Liu, Jiamei Huzheng, Xihong Wang, Xiaopeng An

Abstract read
In one paragraph

Article in Animal biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Phenotypic and Genomic Characterization of theAnimals : an open access journal from MDPI · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xiaolong XuCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, P. R. China.
Yingwei GuoCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, P. R. China.
Miaoyu LiCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, P. R. China.
Quyu DuanCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, P. R. China.
Fu LiCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, P. R. China.
Jintao WangCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, P. R. China.
Nan LiuCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, P. R. China.
Jiamei HuzhengCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, P. R. China.
Xihong WangCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, P. R. China.
Xiaopeng AnCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, P. R. China.
Northwest A&F University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dairy goats are significant livestock that provide high-quality milk sources in the world. The wattles trait is an evident phenotypic character on the neck of a dairy goat, which is considered to be under genetic control. We collected samples of 189 dairy goats, including 94 with wattles and 95 without wattles, from four different farms and multiple dairy goat breeds. The samples were genotyped with the GeneSeek Genomic Profiler Goat 70 K SNP chip. Genome-wide association studies (GWAS) in wattles have identified associations with single nucleotide polymorphisms (SNPs) at chromosome 10. In this area, an extremely strong association locus was assigned to FMN1 (Formin 1) belongs to the formin homology family and is associated with limb deformity, other candidate genes of interest confirmed for wattles were ARHGAP11A (Rho GTPase Activating Protein 11 A) and GJD2 (Gap Junction Protein Delta 2). Meanwhile, we found the presence or absence of wattles had no significant effect on milk yield. This research will provide genetic resources useful to explore genetic factors affecting the trait.

Indexed as

Comb and WattlesGenome-Wide Association StudyAnimalsForminsGenomeGoatsMilkPolymorphism, Single NucleotideForminscandidate genesdairy goatGenome-wide association studywattles

Identifiers

PMID36441629
PMCPMC13353431
OpenAlexW4310157671

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.