ReviewPediatric surgery international2022
Non-operative management of acute appendicitis in children.
Review in Pediatric surgery international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Ultrasound and computed tomography in differentiating between simple and complicated appendicitis in pediatric patients.Pediatric surgery international · 2024Pooled it
- The role of viruses in human acute appendicitis: a systematic literature review.International journal of colorectal disease · 2023Pooled it
- Comparison of Two Antibiotic Combinations for Conservative Treatment of Non-Complicated Appendicitis in Children.Medicina (Kaunas, Lithuania) · 2026Trial
- Expanded Dengue and the Digestive System: A Systematic Review and Meta-Analysis.Tropical medicine and infectious disease · 2026Review
- Non-operative Management of Uncomplicated Appendicitis: A Review of Indications, Safety, and Clinical Algorithms.Cureus · 2026Review
- Microbiological spectrum and antimicrobial resistance patterns in pediatric acute appendicitis: implications for evidence-based empirical therapy.Frontiers in pediatrics · 2026Article
- Efficacy of endoscopic retrograde appendicitis therapy in children with suppurative vs. simple appendicitis: a retrospective cohort study.Frontiers in pediatrics · 2026Article
- Incidentally-detected nonspecific and unusual histopathological findings in childhood appendectomy specimens: a retrospective analysis of 2633 cases.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025Article
- Preoperative inflammatory markers in pediatric appendicitis: associations with disease severity, postoperative recovery, pain, and surgical outcomes.BMC pediatrics · 2025Article
- Conversion Rates and Outcomes of Laparoscopic Appendectomy in Complicated Appendicitis: A Retrospective Study.Cureus · 2025Article
- Case report on appendicitis with intraluminal ascariasis.Radiology case reports · 2025Article
- The Role of Hyponatremia in Identifying Complicated Cases of Acute Appendicitis in the Pediatric Population.Diagnostics (Basel, Switzerland) · 2025Article
- Efficacy of non-operative management of uncomplicated acute appendicitis: initial experience in a resource-limited setting.BMJ paediatrics open · 2025Article
- Comparative evaluation of ultrasound-guided versus operative drainage for pediatric appendicular abscess: Effectiveness, safety and clinical outcomes.Bioinformation · 2025Article
- Review
- The Role of Vascular Cell Adhesion Molecule-1 (VCAM-1) in Predicting Complicated Appendicitis in Children.Diagnostics (Basel, Switzerland) · 2024Article
- The Impact of Protein Glycosylation on the Identification of Patients with Pediatric Appendicitis.International journal of molecular sciences · 2024Article
- Applying an explainable machine learning model might reduce the number of negative appendectomies in pediatric patients with a high probability of acute appendicitis.Scientific reports · 2024Article
- Changes in Levels of Serum Cytokines and Chemokines in Perforated Appendicitis in Children.International journal of molecular sciences · 2024Article
- Colonoscopy in the diagnosis and management of appendiceal disease.World journal of gastrointestinal endoscopy · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Appendicitis is one of the most common surgical emergencies in children and adults. Appendectomy as the standard care has been challenged in the recent years with growing evidence about non-operative treatment as a potential primary treatment in patients presenting with signs and symptoms suggestive of acute appendicitis. This review aims to establish where the recent research stands regarding conservative treatment of acute appendicitis, especially in children. There are several studies that report the potential safety and efficacy of treating acute appendicitis non-operatively. Several studies have challenged the concept of acute appendicitis being a progressive disease that always ends in perforation, rather than a disease that can present as different forms with only a defined number of cases progressing to perforation. The lack of randomized controlled studies is a limitation and well-designed randomized controlled trials are needed to determine the role of non-operative management of acute appendicitis in children.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.