Evidence map›Paper›PMID 36441244›Full record

ArticlePediatric surgery international2022

A predictive scoring system for small diaphragmatic defects in infants with congenital diaphragmatic hernia.

Keita Terui, Kouji Nagata, Masaya Yamoto, Masahiro Hayakawa, Hiroomi Okuyama, Shoichiro Amari, Akiko Yokoi, Taizo Furukawa, Kouji Masumoto, Tadaharu Okazaki and 6 more

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Article in Pediatric surgery international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

16 authors.

Keita TeruiDepartment of Pediatric Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-Ku, Chiba, 260-8677, Japan. kta@cc.rim.or.jp.
Kouji NagataDepartment of Pediatric Surgery, Reproductive and Developmental Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Masaya YamotoDepartment of Pediatric Surgery, Shizuoka Children's Hospital, Shizuoka, Japan.
Masahiro HayakawaDivision of Neonatology, Center for Maternal-Neonatal Care, Nagoya University Hospital, Nagoya, Japan.
Hiroomi OkuyamaDepartment of Pediatric Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Shoichiro AmariDivision of Neonatology, National Center for Child Health and Development, Tokyo, Japan.
Akiko YokoiDepartment of Pediatric Surgery, Kobe Children's Hospital, Kobe, Japan.
Taizo FurukawaDepartment of Pediatric Surgery, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Kouji MasumotoDepartment of Pediatric Surgery, Tsukuba University, Tsukuba, Japan.
Tadaharu OkazakiDepartment of Pediatric Surgery, Juntendo University Urayasu Hospital, Urayasu, Japan.
Noboru InamuraDepartment of Pediatrics, Kindai University, Higashiosaka, Japan.
Katsuaki ToyoshimaDepartment of Neonatology, Kanagawa Children's Medical Center, Yokohama, Japan.
Yuhki KoikeDepartment of Gastrointestinal and Pediatric Surgery, Mie University Graduate School of Medicine, Tsu, Japan.
Manabu OkawadaDepartment of Pediatric General and Urogenital Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Yasunori SatoDepartment of Preventive Medicine and Public Health, Keio University, Tokyo, Japan.
Noriaki UsuiDepartment of Pediatric Surgery, Osaka Women's and Children's Hospital, Izumi, Japan.

Funding

Ministry of Health, Labour and Welfare 20FC1017
6 · The paper itself

Abstract

purposeTo develop a predictive score for small diaphragmatic defects in infants with congenital diaphragmatic hernia (CDH) for determining thoracoscopic surgery indication.

methodsThe Japanese CDH Study Group cohort was randomly divided into derivation (n = 397) and validation (n = 396) datasets. Using logistic regression, a prediction model and weighted scoring system for small diaphragmatic defects were created from derivation dataset and validated with validation dataset.

resultsSix weighted variables were selected: no hydramnios, 1 point; 1 min Apgar score of 5-10, 1 point; apex type of the lung (left lung is detected radiographically in apex area), 1 point; oxygenation index < 8, 1 point; abdominal nasogastric tube (tip of the nasogastric tube is detected radiographically in the abdominal area), 2 points; no right-to-left flow of ductus arteriosus, 1 point. In validation dataset, rates of small diaphragmatic defects for Possible (0-3 points), Probable (4-5 points), and Definite (6-7 points) groups were 36%, 81%, and 94%, respectively (p < 0.001). Additionally, sensitivity, specificity, positive predictive value, and C statistics were 0.78, 0.79, 0.88, 0.76, and 0.45, 0.94, 0.94, 0.70 for Probable and Definite groups, respectively.

conclusionOur scoring system effectively predicted small diaphragmatic defects in infants with CDH.

Indexed as

Ductus Arteriosus, PatentHernias, Diaphragmatic, CongenitalBlood Gas AnalysisHumansInfantProbabilityCongenital abnormalitiesCongenital diaphragmatic herniaDiaphragmMinimally invasive surgical proceduresStatistical models

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.