ArticleVirchows Archiv : an international journal of pathology2023
Morphological characteristics of cardiac myxoma causing embolism: a series of 40 years of experience at a single institute.
Article in Virchows Archiv : an international journal of pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 8 citations in OpenAlex.
- Frequency, Clinical Characteristics, Anatomical Distribution, and Outcomes of Embolic Complications of Cardiac Myxoma in Contemporary Cohorts: Protocol for a Systematic Review and Meta-Analysis.JMIR research protocols · 2026Article
- Early and intermediate outcomes of surgical treatment for atrial myxoma complicated by preoperative ischemic stroke: a retrospective study.European journal of medical research · 2025Article
- Brain metastases in a patient with antecedent of cardiac myxoma: a case report and review of literatureRevista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2024Review
- Left atrial myxoma metastasizing to the brain: a case report and review of literature.Radiation oncology journal · 2024Article
- Vasculitic rash and cerebral emboli in an adolescent with left atrial myxoma.BMJ case reports · 2024Article
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Authors and funding
10 authors at 1 institution in 1 country.
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Abstract
Systemic and cerebral embolisms are serious complications of associated with cardiac myxoma. Embolism risk reportedly depends on the gross and histological morphology. This study is aimed at analyzing the morphologic pattern of excised cardiac myxoma as a high-risk embolic cause. Between 1978 and April 2022, 116 surgical specimens of cardiac myxomas were recorded at the pathology department of our hospital. The tumors were classified into three types based on their macroscopic shapes and external morphology-round-smooth, irregular, and villous-to investigate the embolic complications. Of the 116 specimens, 106 macroscopic images of cardiac myxoma (89% were located in the left atrium) were prepared. Round-smooth types were found in 36 (34.0%) patients, irregular types in 32 (30.2%) patients, and the villous types in 38 (35.8%) patients. Multivariable analysis revealed that a villous external appearance was an independent predictor of embolic events (odds ratio: 8.7; 95% confidence interval: 2.4-42.1; p < 0.001). Villous external appearance of cardiac myxoma was associated with the highest risk of distal embolism.
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