ArticleThe Plant cell2023
Expanded roles and divergent regulation of FAMA in Brachypodium and Arabidopsis stomatal development.
Article in The Plant cell, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 42 citations in OpenAlex.
- What fresh cell is this? Building a single-cell atlas of developing grass leaves in Brachypodium distachyon.The Plant cell · 2026Article
- The developing leaf of the wild grass Brachypodium distachyon at single-cell resolution.The Plant cell · 2026Article
- Targets of SPEECHLESS and FAMA control guard cell division and expansion in the late stomatal lineage.Development (Cambridge, England) · 2026Article
- The MdICE1/MdFAMA-MdTYDC Transcriptional Module Confers Cold Tolerance by Regulating Dopamine Metabolism in Apple.Plant biotechnology journal · 2026Article
- MUTE drives asymmetric divisions to form stomatal subsidiary cells in Crassulaceae succulents.Science advances · 2026Article
- Molecular mechanisms underlying the maintenance of terminal differentiation in Arabidopsis guard cells.Frontiers in plant science · 2026Review
- Regulation of stomatal development by receptor-like kinases and receptor-like proteins inFrontiers in plant science · 2026Review
- Unlocking grass leaf development: foundations for tunable cereal design.The New phytologist · 2025Review
- SPEECHLESS duplication in grasses expands potential for environmental regulation of stomatal development.bioRxiv : the preprint server for biology · 2025Article
- Do grasses have meristemoids?The New phytologist · 2025Article
- Comprehensive genome-wide analysis of bHLH family genes in Nymphaea colorata and molecular characterization of NcTT8.BMC plant biology · 2025Article
- DSD1/ZmICEb regulates stomatal development and drought tolerance in maize.Journal of integrative plant biology · 2025Article
- Co-option and neofunctionalization of stomatal executors for defence against herbivores in Brassicales.Nature plants · 2025Article
- Dual role of BdMUTE during stomatal development in the model grass Brachypodium distachyon.Development (Cambridge, England) · 2024Article
- Stomatal development in the changing climate.Development (Cambridge, England) · 2024Review
- Molecular Mechanisms for Regulating Stomatal Formation across Diverse Plant Species.International journal of molecular sciences · 2024Review
- bHLH transcription factors cooperate with chromatin remodelers to regulate cell fate decisions during Arabidopsis stomatal development.PLoS biology · 2024Article
- Regulation of stomatal development by epidermal, subepidermal and long-distance signals.Plant molecular biology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
Stomata, cellular valves found on the surfaces of aerial plant tissues, present a paradigm for studying cell fate and patterning in plants. A highly conserved core set of related basic helix-loop-helix (bHLH) transcription factors regulates stomatal development across diverse species. We characterized BdFAMA in the temperate grass Brachypodium distachyon and found this late-acting transcription factor was necessary and sufficient for specifying stomatal guard cell fate, and unexpectedly, could also induce the recruitment of subsidiary cells in the absence of its paralogue, BdMUTE. The overlap in function is paralleled by an overlap in expression pattern and by unique regulatory relationships between BdMUTE and BdFAMA. To better appreciate the relationships among the Brachypodium stomatal bHLHs, we used in vivo proteomics in developing leaves and found evidence for multiple shared interaction partners. We reexamined the roles of these genes in Arabidopsis thaliana by testing genetic sufficiency within and across species, and found that while BdFAMA and AtFAMA can rescue stomatal production in Arabidopsis fama and mute mutants, only AtFAMA can specify Brassica-specific myrosin idioblasts. Taken together, our findings refine the current models of stomatal bHLH function and regulatory feedback among paralogues within grasses as well as across the monocot/dicot divide.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.