Evidence map›Paper›PMID 36440853›Full record

ReviewJournal of medicinal chemistry2023

What We Have Gained from Ibogaine: α3β4 Nicotinic Acetylcholine Receptor Inhibitors as Treatments for Substance Use Disorders.

Carolyn J Straub, Lisa E Rusali, Kyle M Kremiller, Andrew P Riley

Open access · greenAbstract readReview
In one paragraph

Review in Journal of medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Total Synthesis of Ervaoffine J and K.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024
    Article
  8. Evolution and diversification of carboxylesterase-like [4+2] cyclases in aspidosperma and iboga alkaloid biosynthesis.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Carolyn J StraubDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0002-8976-5039
Lisa E RusaliDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States.
Kyle M KremillerDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States.
Andrew P RileyDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0002-3878-0597
University of Illinois Chicago · US

Funding

Institutional Career DevelopmentKL2TR002002 · NCATS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PHILLIPS, SHANE A · 2016 to 2024
$6.8M
Research Training in Natural Product Complementary and Integrative HealthT32AT007533 · NCCIH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Joanna E Burdette, JIMMY ORJALA · 2013 to 2026
$4.3M
Synthesis and Evaluation of Alkaloids to Probe Membrane Receptors - Predoctoral SupplementR35GM147005 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Andrew Riley · 2022 to 2026
$2.3M
NCATS NIH HHS KL2 TR002002NCCIH NIH HHS T32 AT007533NIGMS NIH HHS R35 GM147005
6 · The paper itself

Abstract

For decades, ibogaine─the main psychoactive alkaloid found in

Indexed as

IbogaineReceptors, NicotinicSubstance-Related DisordersDose-Response Relationship, DrugHumansIbogaineReceptors, Nicotinic

Identifiers

PMID36440853
PMCPMC10034762
OpenAlexW4310170807

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.