ArticleRheumatology (Oxford, England)2023
Ocular manifestations of ANCA-associated vasculitis.
Article in Rheumatology (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Glandular Manifestations of the Head and Neck in ANCA-Associated Vasculitides: Data from a National Cohort and Systematic Review.Clinical reviews in allergy & immunology · 2025Pooled it
- Unilateral orbital mass as the initial presentation of pediatric antineutrophil cytoplasmic antibody associated vasculitis: eosinophilic granulomatosis with polyangiitis versus granulomatosis with polyangiitis.Journal of ophthalmic inflammation and infection · 2026Article
- Reversible choroidal ischemia as a rare sight-threatening manifestation of microscopic polyangiitis presenting with crescentic glomerulonephritis.BMC nephrology · 2026Article
- Clinician views concerning the prevalence and impact of granulomas on the diagnosis, management, and outcomes of ANCA-associated vasculitis.Rheumatology (Oxford, England) · 2026Article
- Granulomatosis With Polyangiitis Presenting as Pulmonary Nodules: A Case Study and Literature Review.Case reports in immunology · 2026Article
- A multispecialty consensus-based red flag checklist for the early recognition of ANCA-associated vasculitis.Frontiers in immunology · 2026Article
- Scleritis and associated systemic diseases: contribution of systemic examination, follow-up, and additional investigations.Journal of ophthalmic inflammation and infection · 2025Review
- A Red Eye in an Elderly Patient: A Case Report Highlighting the Importance of Urgent Diagnosis.Cureus · 2025Article
- IgG4-related disease and other fibro-inflammatory conditions.Nature reviews. Rheumatology · 2025Review
- [Peripheral ulcerative keratitis with necrotizing scleritis, manifestation of granulomatosis with polyangiitis].Revista medica del Instituto Mexicano del Seguro Social · 2025Article
- Granulomatosis With Polyangiitis (GPA) Presenting With Painless Scleritis and Ocular Hypertension: Case Report.Case reports in immunology · 2025Article
- Article
- Ocular Manifestation of Granulomatosis with Polyangiitis Presenting as Serous Retinal Detachment: A Case Report.Medicina (Kaunas, Lithuania) · 2024Article
- Bilateral Choroidal Detachments Associated with Perinuclear Anti-Neutrophil Cytoplasmic Antibodies (P-ANCA) - Associated Vasculitis.Ocular immunology and inflammation · 2024Article
- Ocular manifestations in ANCA-associated vasculitis: a comprehensive analysis from Chinese medical centers.Clinical rheumatology · 2024Article
- Retinal thickness and microvascular alterations observed by optical coherence tomography in antineutrophil cytoplasmic antibody-associated vasculitis: a cross-sectional study.Quantitative imaging in medicine and surgery · 2024Article
- [Vasculitis of the retina : Clinical aspects, diagnostics, management and treatment].Die Ophthalmologie · 2024Review
- Clinical Image: Scleral melt in granulomatosis with polyangiitis.ACR open rheumatology · 2024Article
- Not Everything Is as It Seems: A Case Series and Overview of Diseases Mimicking Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.Journal of clinical medicine · 2023Article
- Ocular Involvement of Granulomatosis with Polyangiitis.Journal of clinical medicine · 2023Article
Corrections and comments
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Authors and funding
18 authors at 11 institutions in 2 countries.
Funding
Abstract
objectivesANCA-associated vasculitis (AAV) is a group of multisystem diseases that can have several ocular manifestations. There are published data on ocular manifestations of granulomatosis with polyangiitis (GPA), but few for eosinophilic granulomatosis with polyangiitis (EGPA) or microscopic polyangiitis (MPA). There is little information concerning chronicity, complications, and association with other cranial manifestations of AAV.
methodsThis study retrospectively analysed longitudinal multicentre cohorts of individuals with AAV followed between 2006 and 2022. Data included diagnosis, demographics, cranial manifestations of disease, presence of manifestations at onset of disease and/or follow-up, and ocular complications of disease. Univariate and multivariable logistic regression analysis assessed associations across disease manifestations.
resultsData from 1441 patients were analysed, including 395 with EGPA, 876 with GPA, and 170 with MPA. Ocular manifestations were seen within 23.1% of patients: 39 (9.9%) with EGPA, 287 (32.7%) with GPA, and 12 (7.1%) with MPA at any time in the disease course. There were more ocular manifestations at onset (n = 224) than during follow-up (n = 120). The most common disease-related manifestations were conjunctivitis/episcleritis and scleritis. In multivariable analysis, dacryocystitis, lacrimal duct obstruction, and retro-orbital disease were associated with sinonasal manifestations of GPA; ocular manifestations were associated with hearing loss in MPA. The most common ocular complications and/or damage seen were cataracts (n = 168) and visual impairment (n = 195).
conclusionOcular manifestations occur in all forms of AAV, especially in GPA. Clinicians should be mindful of the wide spectrum of ocular disease in AAV, caused by active vasculitis, disease-associated damage, and toxicities of therapy.
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