Evidence map›Paper›PMID 36440544›Full record

SynthesisJournal of neuroscience research2023

Association of CNR1 gene and cannabinoid 1 receptor protein in the human brain.

Kyoungjune Pak, Tatu Kantonen, Laura Pekkarinen, Pirjo Nuutila, Lauri Nummenmaa

Open access · hybridAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of neuroscience research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Kyoungjune PakTurku PET Centre, University of Turku, Turku, Finland.ORCID 0000-0001-5051-1894
Tatu KantonenTurku PET Centre, University of Turku, Turku, Finland.
Laura PekkarinenTurku PET Centre, University of Turku, Turku, Finland.ORCID 0000-0002-5596-0485
Pirjo NuutilaTurku PET Centre, University of Turku, Turku, Finland.ORCID 0000-0001-9597-338X
Lauri NummenmaaTurku PET Centre, University of Turku, Turku, Finland.
University of Turku · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to integrate genomic mapping from brain mRNA atlas with the protein expression from positron emission tomography (PET) scans of type 1 cannabinoid (CB1) receptor and to compare the predictive power of CB1 receptor with those of other neuroreceptor/transporters using a meta-analysis. Volume of distribution (V

Indexed as

CannabinoidsReceptor, Cannabinoid, CB1BrainCyclohexanolsHumansRNA, Messenger3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanolCannabinoidsCNR1 protein, humanCyclohexanolsReceptor, Cannabinoid, CB1RNA, Messengercannabinoid receptormessenger RNApositron emission tomography

Identifiers

PMID36440544
PMCPMC10100072
OpenAlexW4310214780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.